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Literature DB >> 7668169

Scarless wound healing: implications for the aesthetic surgeon.

J Chang¹, J W Siebert, S A Schendel, B H Press, M T Longaker.

Abstract

Recent developments in surgery and basic science research offer aesthetic surgeons the prospect of scarless repair. Studies in fetal wound healing provide both cellular and molecular models of optimal tissue healing without scar formation. Furthermore, craniofacial surgeons may one day operate on cleft lip, cleft palate, and other congenital malformations in utero. Cytokine research has begun to unravel possibilities for modulating the wound-healing inflammatory response in hopes of limiting scar formation. This article presents research on these developments and comments on their possible applications to aesthetic surgery.

Entities: Disease

Mesh：

Substances：
Cytokines

Year: 1995 PMID： 7668169 DOI： 10.1007/bf00451096

Source DB: PubMed Journal: Aesthetic Plast Surg ISSN： 0364-216X Impact factor: 2.326

35 in total

Review 1. Transforming growth factor-beta in disease: the dark side of tissue repair.

Authors: W A Border; E Ruoslahti
Journal: J Clin Invest Date: 1992-07 Impact factor: 14.808

Review 2. Animal models for the study of fetal tissue repair.

Authors: N S Adzick; M T Longaker
Journal: J Surg Res Date: 1991-09 Impact factor: 2.192

3. Studies in fetal wound healing, VI. Second and early third trimester fetal wounds demonstrate rapid collagen deposition without scar formation.

Authors: M T Longaker; D J Whitby; N S Adzick; T M Crombleholme; J C Langer; B W Duncan; S M Bradley; R Stern; M W Ferguson; M R Harrison
Journal: J Pediatr Surg Date: 1990-01 Impact factor: 2.545

Scarless wound healing: implications for the aesthetic surgeon.

Review 1. Transforming growth factor-beta in disease: the dark side of tissue repair.

Review 2. Animal models for the study of fetal tissue repair.

3. Studies in fetal wound healing, VI. Second and early third trimester fetal wounds demonstrate rapid collagen deposition without scar formation.

4. Studies in fetal wound healing: III. Early deposition of fibronectin distinguishes fetal from adult wound healing.

5. The effect of exclusion of amniotic fluid on intra-uterine healing of skin wounds in rabbit foetuses.

6. Fetal wound healing. The ontogeny of scar formation in the non-human primate.

7. In utero cleft lip repair in A/J mice.

8. Immunohistochemical localization of growth factors in fetal wound healing.

9. Endoscopic creation and repair of fetal cleft lip.

Review 10. Growth factors and wound healing: biochemical properties of growth factors and their receptors.

Review 1. Current state of antenatal in utero surgical interventions.

2. Augmenting endogenous Wnt signaling improves skin wound healing.

Review 3. Uterine bleeding: how understanding endometrial physiology underpins menstrual health.