Literature DB >> 766790

Blood-gas changes during induced hypotension with sodium nitroprusside.

J A Wildsmith, G B Drummond, W R MacRae.   

Abstract

A blood-gas study of the respiratory effects of sodium nitroprusside during anaesthesia has shown a marked reduction in PaO2 when the drug was administered. After nitroprusside PaO2 returned to the previous values. It is suggested that the reduction in PaO2 is a result of an increased scatter of ventilation/perfusion relationships in the lung. The reduction in PaO2 was evident during both spontaneous and artificial ventilation. Nitroprusside was associated with a small decrease in actual bicarbonate.

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Year:  1975        PMID： 766790     DOI： 10.1093/bja/47.11.1205

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN： 0007-0912            Impact factor:   9.166


  3 in total

1.  Real-time whole-brain imaging of hemodynamics and oxygenation at micro-vessel resolution with ultrafast wide-field photoacoustic microscopy.

Authors:  Xiaoyi Zhu; Qiang Huang; Anthony DiSpirito; Tri Vu; Qiangzhou Rong; Xiaorui Peng; Huaxin Sheng; Xiling Shen; Qifa Zhou; Laiming Jiang; Ulrike Hoffmann; Junjie Yao
Journal:  Light Sci Appl       Date:  2022-05-17       Impact factor: 20.257

2.  Isoflurane-induced hypotension does not cause impairment in pulmonary gas exchange.

Authors:  J F Nicholas; A M Lam
Journal:  Can Anaesth Soc J       Date:  1984-07

Review 3.  The adult respiratory distress syndrome.

Authors:  J W Biondi; R L Hines; P G Barash; C C Baker; M A Matthay; R A Matthay
Journal:  Yale J Biol Med       Date:  1986 Nov-Dec
  3 in total

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