Literature DB >> 7666652

[Allergic granuloma of the conjunctiva (Splendore-Hoeppli phenomenon)].

O Denk1, J M Rohrbach, M Zierhut, S Thanos.   

Abstract

A 35-year-old woman from Georgia presented with multiple bilateral yellow nodules of the upper bulbar conjunctiva, accompanied by a severe injection of conjunctival vessels. The histologic examination of excisional biopsies showed the characteristic morphology of the Splendore-Hoeppli-phenomenon, which describes granulomas with a necrotized eosinophilic center, surrounded by a ring of epitheloid cells, giant cells and eosinophils. Although nematodes could be identified in only a few lesions, they should always be kept in mind as the causing agent of this condition. No cause of the lesions was found in our patient. The nodules may regress spontaneously. Topical application of corticosteroid eye drops, however, may give relief of symptoms, and sometimes excision of the granulomas will be necessary.

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Year:  1995        PMID: 7666652     DOI: 10.1055/s-2008-1035492

Source DB:  PubMed          Journal:  Klin Monbl Augenheilkd        ISSN: 0023-2165            Impact factor:   0.700


  1 in total

1.  Successful treatment of allergic conjunctival granuloma by topical tacrolimus: A clinicopathologic case report.

Authors:  Alireza Foroutan; Abdolhossein Ghafourian; Abbas Habibi; Pooria Foroutan; Maryam Ashrafkhorasani; Sayyed Amirpooya Alemzadeh
Journal:  Indian J Ophthalmol       Date:  2018-04       Impact factor: 1.848

  1 in total

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