Literature DB >> 7665661

Expression of outer surface proteins A and C of Borrelia burgdorferi in Ixodes ricinus.

V Fingerle1, U Hauser, G Liegl, B Petko, V Preac-Mursic, B Wilske.   

Abstract

A total of 472 field-collected Ixodes ricinus ticks from southern Germany were investigated by immunofluorescence for the presence of Borrelia burgdorferi with a polyvalent rabbit immune serum and with monoclonal antibodies specific for outer surface proteins A and C (OspA and OspC, respectively). Borreliae were detected in 90 ticks with the polyvalent immunofluorescence assay. Infection rates in adults (females, 20.2%; males, 25.2%) were significantly higher than in nymphs (12.1%). OspA was detected in 77 ticks and OspC was detected in only 1 tick with the respective monoclonal antibodies. We therefore conclude that B. burgdorferi in unfed I. ricinus ticks usually expresses OspA and very rarely OspC.

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Year:  1995        PMID： 7665661      PMCID： PMC228287          DOI： 10.1128/jcm.33.7.1867-1869.1995

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  24 in total

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Journal:  Am J Trop Med Hyg       Date:  1994-03       Impact factor: 2.345

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Authors:  A G Barbour; W Burgdorfer; E Grunwaldt; A C Steere
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Authors:  W Burgdorfer; R S Lane; A G Barbour; R A Gresbrink; J R Anderson
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Authors:  J E Craft; D K Fischer; G T Shimamoto; A C Steere
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6.  Phenotypic analysis of outer surface protein C (OspC) of Borrelia burgdorferi sensu lato by monoclonal antibodies: relationship to genospecies and OspA serotype.

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Journal:  J Clin Microbiol       Date:  1995-01       Impact factor: 5.948

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Journal:  J Clin Microbiol       Date:  1993-02       Impact factor: 5.948

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Authors:  B Wilske; V Preac-Mursic; S Jauris; A Hofmann; I Pradel; E Soutschek; E Schwab; G Will; G Wanner
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Authors:  T G Schwan; J Piesman
Journal:  J Clin Microbiol       Date:  2000-01       Impact factor: 5.948

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