| Literature DB >> 7665636 |
M Imai1, T Hayashi, M Kondo, T Saito, A Ito, M Hayami, K Nishioka.
Abstract
The interpretation of dual seroreactivity with human immunodeficiency virus type 1 (HIV-1) and HIV-2 in blood samples is a serious problem facing AIDS researchers worldwide. Some samples of sera from HIV-1-infected patients showed a serological cross-reaction with HIV-2, causing confusion regarding the serodiagnosis. Therefore, we tried to differentiate these serum samples from those containing real mixed infections with both types of virus. Sera from patients with HIV-1 infections with HIV-2 cross-reacting antibody in Japan were distinguished from sera from patients with mixed infections with HIV-1 and HIV-2 in West Africa by our serological cross-absorption test, which proved to be highly specific and useful for serodiagnosis.Entities:
Keywords: Antibodies; Biology; Diseases; Examinations And Diagnoses; Hiv Infections; Hiv Serodiagnosis; Immunity; Immunologic Factors; Laboratory Examinations And Diagnoses; Laboratory Procedures; Physiology; Research Report; Viral Diseases
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Year: 1995 PMID: 7665636 PMCID: PMC228257 DOI: 10.1128/jcm.33.7.1727-1729.1995
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948