Literature DB >> 7662893

Cyclin E is expressed in neurons and forms complexes with cdk5.

M Miyajima1, H O Nornes, T Neuman.   

Abstract

Expression of cyclin dependent kinase cdk5 and its regulator p35 has been shown in the cytoplasm of adult neurons. Here we demonstrate that another potential regulator of cdk5, cyclin E, is expressed in the nervous system and forms complexes with cdk5. Western blot analyses identifies expression of two forms of cyclin E in the mouse nervous system with the 56 kDa form mainly expressed in neurons and 51 kDa form expressed in astrocytes and oligodendrocytes.

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Year:  1995        PMID： 7662893     DOI： 10.1097/00001756-199505300-00014

Source DB:  PubMed          Journal:  Neuroreport        ISSN： 0959-4965            Impact factor:   1.837


  12 in total

1.  Explant-induced reactivation of herpes simplex virus occurs in neurons expressing nuclear cdk2 and cdk4.

Authors:  Luis M Schang; Andrew Bantly; Priscilla A Schaffer
Journal:  J Virol       Date:  2002-08       Impact factor: 5.103

2.  Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation.

Authors:  Junko Odajima; Zachary P Wills; Yasmine M Ndassa; Miho Terunuma; Karla Kretschmannova; Tarek Z Deeb; Yan Geng; Sylwia Gawrzak; Isabel M Quadros; Jennifer Newman; Manjusri Das; Marie E Jecrois; Qunyan Yu; Na Li; Frederic Bienvenu; Stephen J Moss; Michael E Greenberg; Jarrod A Marto; Piotr Sicinski
Journal:  Dev Cell       Date:  2011-09-22       Impact factor: 12.270

3.  The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells.

Authors:  W Poluha; D K Poluha; B Chang; N E Crosbie; C M Schonhoff; D L Kilpatrick; A H Ross
Journal:  Mol Cell Biol       Date:  1996-04       Impact factor: 4.272

4.  Retinoblastoma protein modulates the inverse relationship between cellular proliferation and elastogenesis.

Authors:  Sanjana Sen; Severa Bunda; Junyan Shi; Andrew Wang; Thomas F Mitts; Aleksander Hinek
Journal:  J Biol Chem       Date:  2011-08-31       Impact factor: 5.157

5.  Two cyclin-dependent kinase pathways are essential for polarized trafficking of presynaptic components.

Authors:  Chan-Yen Ou; Vivian Y Poon; Celine I Maeder; Shigeki Watanabe; Emily K Lehrman; Amy K Y Fu; Mikyoung Park; Wing-Yu Fu; Erik M Jorgensen; Nancy Y Ip; Kang Shen
Journal:  Cell       Date:  2010-05-28       Impact factor: 41.582

6.  Proteomic analysis of the human cyclin-dependent kinase family reveals a novel CDK5 complex involved in cell growth and migration.

Authors:  Shuangbing Xu; Xu Li; Zihua Gong; Wenqi Wang; Yujing Li; Binoj Chandrasekharan Nair; Hailong Piao; Kunyu Yang; Gang Wu; Junjie Chen
Journal:  Mol Cell Proteomics       Date:  2014-08-05       Impact factor: 5.911

Review 7.  The neuronal cell cycle as a mechanism of pathogenesis in Alzheimer's disease.

Authors:  Antonio Currais; Tibor Hortobágyi; Salvador Soriano
Journal:  Aging (Albany NY)       Date:  2009-04-28       Impact factor: 5.682

8.  Cell cycle independent interaction of CDC2 with the centrosome, which is associated with the nuclear matrix-intermediate filament scaffold.

Authors:  S M Pockwinse; G Krockmalnic; S J Doxsey; J Nickerson; J B Lian; A J van Wijnen; J L Stein; G S Stein; S Penman
Journal:  Proc Natl Acad Sci U S A       Date:  1997-04-01       Impact factor: 11.205

Review 9.  Cdk5 and the non-catalytic arrest of the neuronal cell cycle.

Authors:  Jie Zhang; Karl Herrup
Journal:  Cell Cycle       Date:  2008-11-18       Impact factor: 4.534

Review 10.  Cyclin E in normal physiology and disease states.

Authors:  Chen Chu; Yan Geng; Yu Zhou; Piotr Sicinski
Journal:  Trends Cell Biol       Date:  2021-05-27       Impact factor: 21.167
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