Literature DB >> 7662096

Thymic emigration: conveyor belts or lucky dips?

R Scollay1, D I Godfrey.   

Abstract

The thymic medulla has always seemed a rather uncomplicated compartment, simply storing mature thymocytes until they are exported to the peripheral lymphoid organs. However, as discussed here by Roland Scollay and Dale Godfrey, a careful look at recent data suggests that events in the medulla may be more complex and protracted than previously thought.

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Year:  1995        PMID: 7662096     DOI: 10.1016/0167-5699(95)80179-0

Source DB:  PubMed          Journal:  Immunol Today        ISSN: 0167-5699


  37 in total

1.  Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist.

Authors:  Hugh Rosen; Christopher Alfonso; Charles D Surh; Michael G McHeyzer-Williams
Journal:  Proc Natl Acad Sci U S A       Date:  2003-09-03       Impact factor: 11.205

2.  A unique lymphotoxin {alpha}beta-dependent pathway regulates thymic emigration of V{alpha}14 invariant natural killer T cells.

Authors:  Ann Sophie Franki; Katrien Van Beneden; Pieter Dewint; Kirsten J L Hammond; Stijn Lambrecht; Georges Leclercq; Mitchell Kronenberg; Dieter Deforce; Dirk Elewaut
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-02       Impact factor: 11.205

Review 3.  Thymic T-cell development in allogeneic stem cell transplantation.

Authors:  Werner Krenger; Bruce R Blazar; Georg A Holländer
Journal:  Blood       Date:  2011-03-22       Impact factor: 22.113

4.  Two distinct pathways of positive selection for thymocytes.

Authors:  K Akashi; M Kondo; I L Weissman
Journal:  Proc Natl Acad Sci U S A       Date:  1998-03-03       Impact factor: 11.205

5.  Galectin-1, an endogenous lectin produced by thymic epithelial cells, induces apoptosis of human thymocytes.

Authors:  N L Perillo; C H Uittenbogaart; J T Nguyen; L G Baum
Journal:  J Exp Med       Date:  1997-05-19       Impact factor: 14.307

6.  Developmental pathway of CD4+CD8- medullary thymocytes during mouse ontogeny and its defect in Aire-/- mice.

Authors:  Juan Li; Yan Li; Jin-Yan Yao; Rong Jin; Ming-Zhao Zhu; Xiao-Ping Qian; Jun Zhang; Yang-Xin Fu; Li Wu; Yu Zhang; Wei-Feng Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2007-11-05       Impact factor: 11.205

7.  Impaired thymic selection and abnormal antigen-specific T cell responses in Foxn1(Δ/Δ) mutant mice.

Authors:  Shiyun Xiao; Nancy R Manley
Journal:  PLoS One       Date:  2010-11-04       Impact factor: 3.240

8.  A NUP98-HOXD13 fusion gene impairs differentiation of B and T lymphocytes and leads to expansion of thymocytes with partial TCRB gene rearrangement.

Authors:  Chul Won Choi; Yang Jo Chung; Christopher Slape; Peter D Aplan
Journal:  J Immunol       Date:  2009-10-19       Impact factor: 5.422

9.  Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5.

Authors:  Ryan D Schulteis; Haiyan Chu; Xuezhi Dai; Yuhong Chen; Brandon Edwards; Dipica Haribhai; Calvin B Williams; Subramaniam Malarkannan; Martin J Hessner; Sanja Glisic-Milosavljevic; Srikanta Jana; Edward J Kerschen; Soumitra Ghosh; Demin Wang; Anne E Kwitek; Ake Lernmark; Jack Gorski; Hartmut Weiler
Journal:  Blood       Date:  2008-09-16       Impact factor: 22.113

10.  A cellular automata-based mathematical model for thymocyte development.

Authors:  Hallan Souza-e-Silva; Wilson Savino; Raúl A Feijóo; Ana Tereza Ribeiro Vasconcelos
Journal:  PLoS One       Date:  2009-12-09       Impact factor: 3.240

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