Literature DB >> 7661469

Hepatic hemorrhage and the HELLP syndrome: a surgeon's perspective.

J T Stevenson1, D J Graham.   

Abstract

Hypertension-induced hepatic disease is a common cause of abdominal pain and liver function test abnormalities in the pregnant patient. Liver hemorrhage and rupture, in turn, are the most unusual and serious complications of preeclamptic/eclamptic or HELLP (Hemolysis Elevated Liver enzymes and Low Platelet count) associated disease. Should a liver hematoma be documented, management must be aggressive, with treatment of hypertension, correction of any coagulopathy, and prompt delivery of the child. Rupture remains a surgical emergency with control of bleeding based on trauma principles. Postoperative care is difficult, with a propensity toward multiple system organ failure. With an aggressive multidisciplinary approach to the management of these patients, mortality rates have been decreased by fifty per cent. Subsequent pregnancies appear to carry no increased risk of liver rupture over the general population but should be followed carefully by a high-risk obstetrician.

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Year:  1995        PMID: 7661469

Source DB:  PubMed          Journal:  Am Surg        ISSN: 0003-1348            Impact factor:   0.688


  7 in total

Review 1.  HELLP syndrome as a cause of unexpected rapid maternal death--a case report and review of the literature.

Authors:  M Simic; M Tasic; G Stojiljkovic; D Draskovic; R Vukovic
Journal:  Int J Legal Med       Date:  2004-11-11       Impact factor: 2.686

2.  Presentation of laboratory and sonoclot variables using principal component analysis: identification of hypo- and hypercoagulation in the HELLP syndrome.

Authors:  John J Liszka-Hackzell; Ulf Schött
Journal:  J Clin Monit Comput       Date:  2004-08       Impact factor: 2.502

3.  Liver packing during elective surgery: an option that can be considered.

Authors:  Marc Antoine Allard; Federica Dondero; Daniel Sommacale; Safi Dokmak; Jacques Belghiti; Olivier Farges
Journal:  World J Surg       Date:  2011-11       Impact factor: 3.352

4.  Spontaneous hepatic rupture: a report of five cases.

Authors:  R Mascarenhas; J Mathias; R Varadarajan; J Geoghegan; O Traynor
Journal:  HPB (Oxford)       Date:  2002       Impact factor: 3.647

5.  Multimodality imaging of hepato-biliary disorders in pregnancy: a pictorial essay.

Authors:  Eugene M W Ong; Jennifer S Drukteinis; Hope E Peters; Koenraad J Mortelé
Journal:  Emerg Radiol       Date:  2009-02-19

6.  Spontaneous hepatic rupture in a patient with peliosis hepatis: A report of one case.

Authors:  Daniele Sommacale; Elisa Palladino; Esther L Tamby; Marie Danielle Diebold; Ali Reza Kianmanesh
Journal:  Int J Surg Case Rep       Date:  2013-02-17

7.  Hepatic rupture in HELLP syndrome.

Authors:  Catarina Moura; Luís Amaral; Joana Mendes; Rui Quintanilha; Francisco Melo Bento; Maria Inês Leite; António Melo
Journal:  J Surg Case Rep       Date:  2019-10-17
  7 in total

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