PURPOSE/ METHODS: Activated protein C resistance was recently described as a major cause of venous thrombosis. We observed a central retinal vein thrombosis in a woman with activated protein C resistance. RESULTS/ CONCLUSION: DNA analysis showed the patient to be heterozygous for the factor V gene mutation, which is related to activated protein C resistance. Patients with retinal vein thrombosis should be examined for activated protein C resistance.
PURPOSE/ METHODS: Activated protein C resistance was recently described as a major cause of venous thrombosis. We observed a central retinal vein thrombosis in a woman with activated protein C resistance. RESULTS/ CONCLUSION: DNA analysis showed the patient to be heterozygous for the factor V gene mutation, which is related to activated protein C resistance. Patients with retinal vein thrombosis should be examined for activated protein C resistance.
Authors: M Cahill; M Karabatzaki; R Meleady; H Refsum; P Ueland; D Shields; D Mooney; I Graham Journal: Br J Ophthalmol Date: 2000-02 Impact factor: 4.638
Authors: A Ferreira-Gonzalez; L M Fisher; C M Lehman; M H Langley; D H Lofland; Q Xia; N X Nguyen; D Modesto; J B Willoughby; D S Wilkinson; C T Garrett Journal: J Clin Lab Anal Date: 1997 Impact factor: 2.352