| Literature DB >> 7660640 |
P Flanagan1, L McAlpine, S J Ramskill, A G Smith, R Eglin, J V Parry, P P Mortimer.
Abstract
A combined immunoassay for the simultaneous detection of antibodies to HIV-1/2 and HTLV-I/II (Bioelisa, Launch Diagnostics) has been evaluated to determine its suitability for routine use in blood screening. 84,222 donations were tested from 76,452 donors. One HIV- and 1 HTLV-1-positive donor were identified. The specificity was 99.7%, and the sensitivity for anti-HIV-1, anti-HIV-2, and anti-HTLV-1 on 173 positive sera was 100%; 2 of 25 anti-HTLV-II-positive sera were non-reactive. Although the specificity of the assay is not as high as that of HIV-1/2 kits currently in UK transfusion use, the information gained about donor HTLV antibody status makes the test an attractive alternative to them.Entities:
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Year: 1995 PMID： 7660640 DOI： 10.1111/j.1423-0410.1995.tb02576.x
Source DB: PubMed Journal: Vox Sang ISSN： 0042-9007 Impact factor: 2.144