Literature DB >> 766016

Inhibition by nalidixic acid of post-uv survival of Escherichia coli.

M Nishida, N Nakamura, K L Yielding.   

Abstract

Nalidixate inhibited the post-uv survival of E. coli B. TAU-bar and Ts-7, but not Bs-1 or B/r when included in the plating medium. Removal of the drug sensitivity by photoreactivation was consistent with pyrimidine dimers as the target for the effect. Nalidixate did not inhibit liquid-holding recovery from uv when included in the holding medium, but survival was inhibited if the drug was in the subsequent plating medium. In fact, there was an actual increase in the number of nonsurvivors due to the drug following a period of holding.

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Year:  1976        PMID: 766016     DOI: 10.3181/00379727-151-39190

Source DB:  PubMed          Journal:  Proc Soc Exp Biol Med        ISSN: 0037-9727


  2 in total

1.  Enhancement of post-ultraviolet killing in Escherichia coli K-12 through the action of gyrase inhibitors: evidence for associated gyrase-recBC deoxyribonuclease function.

Authors:  M A Purdy; K L Yielding
Journal:  Antimicrob Agents Chemother       Date:  1979-09       Impact factor: 5.191

2.  Nalidixic acid inhibition of post-ultraviolet recovery in Escherichia coli K-12: requirement for recBC function.

Authors:  M A Purdy; K L Yeilding
Journal:  Antimicrob Agents Chemother       Date:  1976-07       Impact factor: 5.191

  2 in total

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