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Literature DB >> 7659293

Analysis of the phase shifting effects of gastrin releasing peptide when microinjected into the suprachiasmatic region.

H E Albers¹, C F Gillespie, T O Babagbemi, K L Huhman.

Abstract

The role of gastrin releasing peptide (GRP) in phase shifting circadian rhythms was investigated. Microinjection of GRP into the suprachiasmatic region (SCN) region produced only small changes in the phase of free-running circadian activity rhythms in hamsters housed in constant darkness. However, co-administration of GRP with vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI) produced significantly larger phase delays than GRP alone. These data support the hypothesis that GRP interacts with VIP and PHI within the SCN to induce phase shifts of circadian rhythms.

Entities: Chemical Gene

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Year: 1995 PMID： 7659293 DOI： 10.1016/0304-3940(95)11559-1

Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046

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Cited

16 in total

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Review 2. Circuit development in the master clock network of mammals.

Authors: Vania Carmona-Alcocer; Kayla E Rohr; Deborah A M Joye; Jennifer A Evans
Journal: Eur J Neurosci Date: 2018-12-05 Impact factor: 3.386

3. Endogenous peptide discovery of the rat circadian clock: a focused study of the suprachiasmatic nucleus by ultrahigh performance tandem mass spectrometry.

Authors: Ji Eun Lee; Norman Atkins; Nathan G Hatcher; Leonid Zamdborg; Martha U Gillette; Jonathan V Sweedler; Neil L Kelleher
Journal: Mol Cell Proteomics Date: 2009-11-10 Impact factor: 5.911

10. Gastrin-releasing peptide mediates light-like resetting of the suprachiasmatic nucleus circadian pacemaker through cAMP response element-binding protein and Per1 activation.

Authors: Karen L Gamble; Gregg C Allen; Tongrong Zhou; Douglas G McMahon
Journal: J Neurosci Date: 2007-10-31 Impact factor: 6.167

Analysis of the phase shifting effects of gastrin releasing peptide when microinjected into the suprachiasmatic region.

1. The effects of aging and chronic fluoxetine treatment on circadian rhythms and suprachiasmatic nucleus expression of neuropeptide genes and 5-HT1B receptors.

Review 2. Circuit development in the master clock network of mammals.

3. Endogenous peptide discovery of the rat circadian clock: a focused study of the suprachiasmatic nucleus by ultrahigh performance tandem mass spectrometry.

4. Laser-capture microdissection and transcriptional profiling of the dorsomedial nucleus of the hypothalamus.

Review 5. The clock shop: coupled circadian oscillators.

6. Circadian integration of glutamatergic signals by little SAAS in novel suprachiasmatic circuits.

7. Circadian trafficking of calbindin-ir in fibers of SCN neurons.

8. Diurnal regulation of the gastrin-releasing peptide receptor in the mouse circadian clock.

9. Phenotype matters: identification of light-responsive cells in the mouse suprachiasmatic nucleus.

10. Gastrin-releasing peptide mediates light-like resetting of the suprachiasmatic nucleus circadian pacemaker through cAMP response element-binding protein and Per1 activation.