Literature DB >> 7658429

(5aR,11bS)-4,5,5a,6,7,11b-hexahydro-2-propyl-3-thia-5-azacyclopent-1- ena[c]-phenanthrene-9,10-diol (A-86929): a potent and selective dopamine D1 agonist that maintains behavioral efficacy following repeated administration and characterization of its diacetyl prodrug (ABT-431).

M R Michaelides1, Y Hong, S DiDomenico, K E Asin, D R Britton, C W Lin, M Williams, K Shiosaki.   

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Year:  1995        PMID: 7658429     DOI: 10.1021/jm00018a002

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  11 in total

1.  The effects of central aromatic amino acid DOPA decarboxylase inhibition on the motor actions of L-DOPA and dopamine agonists in MPTP-treated primates.

Authors:  S A Treseder; M Jackson; P Jenner
Journal:  Br J Pharmacol       Date:  2000-04       Impact factor: 8.739

2.  Analogues of doxanthrine reveal differences between the dopamine D1 receptor binding properties of chromanoisoquinolines and hexahydrobenzo[a]phenanthridines.

Authors:  Juan Pablo Cueva; Benjamin R Chemel; Jose I Juncosa; Markus A Lill; Val J Watts; David E Nichols
Journal:  Eur J Med Chem       Date:  2011-12-03       Impact factor: 6.514

Review 3.  Pharmacogenetic tools for the development of target-oriented cognitive-enhancing drugs.

Authors:  José A Apud; Daniel R Weinberger
Journal:  NeuroRx       Date:  2006-01

Review 4.  Novel Dopamine Therapeutics for Cognitive Deficits in Schizophrenia.

Authors:  Amy F T Arnsten; Ragy R Girgis; David L Gray; Richard B Mailman
Journal:  Biol Psychiatry       Date:  2016-01-18       Impact factor: 13.382

Review 5.  Dopamine receptor signaling and current and future antipsychotic drugs.

Authors:  Kevin N Boyd; Richard B Mailman
Journal:  Handb Exp Pharmacol       Date:  2012

6.  Effects of the D1 dopamine receptor agonist dihydrexidine (DAR-0100A) on working memory in schizotypal personality disorder.

Authors:  Daniel R Rosell; Lauren C Zaluda; Margaret M McClure; M Mercedes Perez-Rodriguez; K Sloan Strike; Deanna M Barch; Philip D Harvey; Ragy R Girgis; Erin A Hazlett; Richard B Mailman; Anissa Abi-Dargham; Jeffrey A Lieberman; Larry J Siever
Journal:  Neuropsychopharmacology       Date:  2014-07-30       Impact factor: 7.853

7.  D1, not D2, dopamine receptor activation dramatically improves MPTP-induced parkinsonism unresponsive to levodopa.

Authors:  Richard B Mailman; Yang Yang; Xuemei Huang
Journal:  Eur J Pharmacol       Date:  2020-12-03       Impact factor: 4.432

8.  Dopamine D1R Receptor Stimulation as a Mechanistic Pro-cognitive Target for Schizophrenia.

Authors:  Anissa Abi-Dargham; Jonathan A Javitch; Mark Slifstein; Alan Anticevic; Monica E Calkins; Youngsun T Cho; Clara Fonteneau; Roberto Gil; Ragy Girgis; Raquel E Gur; Ruben C Gur; Jack Grinband; Joshua Kantrowitz; Christian Kohler; John Krystal; John Murray; Mohini Ranganathan; Nicole Santamauro; Jared Van Snellenberg; Zailyn Tamayo; Daniel Wolf; David Gray; Jeffrey Lieberman
Journal:  Schizophr Bull       Date:  2022-01-21       Impact factor: 7.348

Review 9.  The Discovery of Novel Selective D1 Dopaminergic Agonists: A-68930, A-77636, A-86929, and ABT-413.

Authors:  Yvonne Connolly Martin
Journal:  Int J Med Chem       Date:  2011-03-24

10.  A quantitative way to estimate clinical off-target effects for human membrane brain targets in CNS research and development.

Authors:  Athan Spiros; Hugo Geerts
Journal:  J Exp Pharmacol       Date:  2012-04-30
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