| Literature DB >> 7657769 |
S W Ngai1, O S Tang, T Lao, P C Ho, H K Ma.
Abstract
Intravaginal misoprostol has been shown to be effective for cervical priming before a surgically induced abortion. The objective was to investigate the effectiveness of oral misoprostol in cervical dilatation prior to vacuum aspiration between the 6th and 12th weeks of pregnancy. The results showed that in nulliparous patients, the median cervical dilatation in the treatment group (7.8 mm) was significantly greater than that in the placebo group (3.7 mm). In multiparous patients, the difference was also statistically significant (9.8 versus 6.0 mm). The ease of dilatation, assessed subjectively by the operating surgeons, was significantly improved in the treatment group. There was also a significant reduction in the duration of the operation and in the mean blood loss in the treatment group. The side-effects encountered in the treatment group were mild and well accepted by the women. Oral misoprostol is an effective and safe method for cervical dilatation prior to vacuum aspiration in first trimester pregnancy.Entities:
Keywords: Abortion, Drug Induced; Abortion, Induced; Asia; Biology; Case Control Studies; Cervical Dilatation; Cervical Effects; Cervix; Clinical Research; Demographic Factors; Developing Countries; Eastern Asia; Endocrine System; Family Planning; Fertility; Fertility Control, Postconception; Fertility Measurements; Genitalia; Genitalia, Female; Hong Kong; Misoprostol; Parity; Physiology; Population; Population Dynamics; Prostaglandins; Prostaglandins, Synthetic; Research Methodology; Research Report; Studies; Treatment; Urogenital System; Uterus; Vacuum Aspiration
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Year: 1995 PMID： 7657769 DOI： 10.1093/oxfordjournals.humrep.a136122
Source DB: PubMed Journal: Hum Reprod ISSN： 0268-1161 Impact factor: 6.918