Antigenic activity and mobility of bovine pituitary hormones.

The antigenic activity and mobility of bovine pituitary hormones; follicle stimulating hormone (FSH), growth hormone (GH), luteinizing hormone (LH), thyroid stimulating hormone (TSH), adrenocorticotropic hormone (ACTH) and melanophore stimulating hormone (MSH) were studied with the aid of agar gel diffusion and electrophoresis. MSH and ACTH were the only hormones not demonstrating antigenicity. Tests by electrophoresis showed "gamma" mobility of the pituitary hormones exhibiting antigenic activity. The observation of antigenic determinants exhibiting identity with immunoglobulins suggests that the bovine pituitary gland houses immunoglobulin molecule and the various pituitary hormones.