Literature DB >> 7655801

Surgical wound healing complicated by Aspergillus infection in a nonimmunocompromised host.

L L Anderson1, M B Giandoni, R A Keller, W J Grabski.   

Abstract

BACKGROUND: An unusual complication of cutaneous surgery and its management is presented. Aspergillus flavus was identified from a nonhealing surgical wound of the ear undergoing cartilaginous necrosis in an immunocompetent host.
OBJECTIVE: We wish to alert clinicians that Aspergillus may infect surgical wounds of the ear causing significant morbidity.
METHOD: A healthy man underwent Mohs micrographic surgery for invasive Bowen's disease of the ear. Due to the size and location of the defect it was allowed to heal by secondary intent. The patient developed inflammation and subsequent destruction of the ear cartilage. Aspergillus was demonstrated by touch preps and cultured from swabs and tissue from the necrotic wound.
RESULTS: In spite of aggressive topical and oral antifungal therapy severe distortion of the pinna occurred, resulting in surgical removal of the upper two-thirds of the ear.
CONCLUSIONS: In the presence of cartilage necrosis following surgery on the ear, Aspergillus infection should be considered. Early aggressive management with surgical debridement, and topical and oral antifungal therapy may prevent destruction of the cartilage and a significant cosmetic defect.

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Year:  1995        PMID: 7655801     DOI: 10.1111/j.1524-4725.1995.tb00301.x

Source DB:  PubMed          Journal:  Dermatol Surg        ISSN: 1076-0512            Impact factor:   3.398


  3 in total

Review 1.  Cutaneous aspergillosis.

Authors:  J A van Burik; R Colven; D H Spach
Journal:  J Clin Microbiol       Date:  1998-11       Impact factor: 5.948

2.  Free flap coverage of extensive soft tissue defect in cutaneous aspergillosis: a case report.

Authors:  Chan Yeong Heo; Seok Chan Eun; Rong Min Baek; Kyung Won Minn
Journal:  J Korean Med Sci       Date:  2008-10       Impact factor: 2.153

Review 3.  Aspergillus Genus and Its Various Human Superficial and Cutaneous Features.

Authors:  Yassine Merad; Hichem Derrar; Zoubir Belmokhtar; Malika Belkacemi
Journal:  Pathogens       Date:  2021-05-23
  3 in total

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