| Literature DB >> 765499 |
E J Sanford, J R Drago, T J Rohner, R Santen, A Lipton.
Abstract
Complete adrenal suppression with aminoglutethimide has been accomplished in 7 patients with progressive stage D carcinoma of the prostate who had become refractory to orchiectomy and the administration of exogenous estrogens. A favorable response was noted in 3 patients. These preliminary results indicate that this agent may be as useful as surgical adrenalectomy in the treatment of progressive prostatic carcinoma. A brief discussion of the pharmacology of this agent, its mode of administration and the side effects are presented.Entities:
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Year: 1976 PMID： 765499 DOI： 10.1016/s0022-5347(17)59121-1
Source DB: PubMed Journal: J Urol ISSN： 0022-5347 Impact factor: 7.450