Literature DB >> 7653152

Tn antigens and their significance in oncology.

E Lisowska1.   

Abstract

Tn and sialyl-Tn carbohydrate structures, first identified in glycophorins of persons with the rare Tn syndrome, were found to be present on the surface of most cancer cells. In this article, the studies on Tn and sialyl-Tn antigens as diagnostic and prognostic tumor markers and as immunogens in vaccines for cancer immunotherapy are shortly reviewed.

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Year:  1995        PMID： 7653152

Source DB:  PubMed          Journal:  Acta Biochim Pol        ISSN： 0001-527X            Impact factor:   2.149


  2 in total

Review 1.  Tn and sialyl-Tn antigens, aberrant O-glycomics as human disease markers.

Authors:  Tongzhong Ju; Yingchun Wang; Rajindra P Aryal; Sylvain D Lehoux; Xiaokun Ding; Matthew R Kudelka; Christopher Cutler; Junwei Zeng; Jianmei Wang; Xiaodong Sun; Jamie Heimburg-Molinaro; David F Smith; Richard D Cummings
Journal:  Proteomics Clin Appl       Date:  2013-09-09       Impact factor: 3.494

Review 2.  Targeting glycans for CAR therapy: The advent of sweet CARs.

Authors:  Zoe Raglow; Mary Kathryn McKenna; Challice L Bonifant; Wenjing Wang; Marina Pasca di Magliano; Johannes Stadlmann; Josef M Penninger; Richard D Cummings; Malcolm K Brenner; David M Markovitz
Journal:  Mol Ther       Date:  2022-07-12       Impact factor: 12.910
  2 in total

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