Literature DB >> 7649677

Myocardial ischemia induced by topical use of 5-fluorouracil.

Y Rozenman1, J Gurewich, M S Gotsman.   

Abstract

An 85-year-old woman, with known stable angina pectoris, was prescribed 5-fluorouracil cream to treat a small basal cell carcinoma on the forehead. Half an hour after application the patient developed her typical ischemic pain which persisted for 2 hours. Rechallenge, during hospitalization, resulted in recurrence of symptoms that were effectively controlled with sublingual isosorbide dinitrate. Prophylactic therapy with nitroglycerin patch enabled further use of the 5-fluorouracil cream for the next month.

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Year:  1995        PMID: 7649677     DOI: 10.1016/0167-5273(95)02314-m

Source DB:  PubMed          Journal:  Int J Cardiol        ISSN: 0167-5273            Impact factor:   4.164


  6 in total

1.  Coronary artery spasm induced by 5-fluorouracil.

Authors:  P Alter; M Herzum; J R Schaefer; B Maisch
Journal:  Z Kardiol       Date:  2005-01

Review 2.  Cardiotoxicity of the antiproliferative compound fluorouracil.

Authors:  K Becker; J F Erckenbrecht; D Häussinger; T Frieling
Journal:  Drugs       Date:  1999-04       Impact factor: 9.546

3.  Total body topical 5-fluorouracil for extensive non-melanoma skin cancer.

Authors:  Serge van Ruth; Frank G A Jansman; Cornelis J Sanders
Journal:  Pharm World Sci       Date:  2006-09-27

Review 4.  Pharmacological treatments for basal cell carcinoma.

Authors:  Seongmu Lee; Dinesh Selva; Shyamala C Huilgol; Robert A Goldberg; Igal Leibovitch
Journal:  Drugs       Date:  2007       Impact factor: 9.546

5.  Aloe vera induced biomimetic assemblage of nucleobase into nanosized particles.

Authors:  Arun Chauhan; Swaleha Zubair; Asif Sherwani; Mohammad Owais
Journal:  PLoS One       Date:  2012-03-05       Impact factor: 3.240

6.  Pre-clinical evidences for the efficacy of tryptanthrin as a potent suppressor of skin cancer.

Authors:  Mohan Shankar G; Vijai V Alex; Amrutha Nisthul A; Smitha V Bava; Sankar Sundaram; Archana P Retnakumari; Sadasivan Chittalakkottu; Ruby John Anto
Journal:  Cell Prolif       Date:  2019-10-30       Impact factor: 6.831

  6 in total

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