Literature DB >> 7649281

Molecular cloning and sequence analysis of human preprocathepsin C.

A Paris1, B Strukelj, J Pungercar, M Renko, I Dolenc, V Turk.   

Abstract

A cDNA clone (C1) coding for human preprocathepsin C was isolated from a human ileum cDNA library using a rat kidney-derived RT-PCR probe and its complete nucleotide sequence determined. The full-length 1857 bp sequence codes for a protein of 463 amino acid residues with a calculated molecular mass of 51848 Da. Comparison of the deduced amino acid sequence with that of rat preprocathepsin C indicates an 87.5% identity. A multiple alignment of the deduced cathepsin C sequence of 233 residues which, by analogy to other cystein proteinases, corresponds to the mature protein, confirms that human cathepsin C belongs to the papain superfamily.

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Year:  1995        PMID： 7649281     DOI： 10.1016/0014-5793(95)00777-7

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  16 in total

1.  Mutations of the cathepsin C gene are responsible for Papillon-Lefèvre syndrome.

Authors:  T C Hart; P S Hart; D W Bowden; M D Michalec; S A Callison; S J Walker; Y Zhang; E Firatli
Journal:  J Med Genet       Date:  1999-12       Impact factor: 6.318

2.  Papillon-Lefevre Syndrome In An Adolescent Female: A Case Study.

Authors:  M J Jijin; H P Jaishankar; Veena Sathya Narayaran; Krupashankar Rangaswamy; Kavitha Ankanathapura Puthaswamy
Journal:  J Clin Diagn Res       Date:  2015-05-01

3.  Identification of cathepsin C mutations in ethnically diverse papillon-Lefèvre syndrome patients.

Authors:  P S Hart; Y Zhang; E Firatli; C Uygur; M Lotfazar; M D Michalec; J J Marks; X Lu; B J Coates; W K Seow; R Marshall; D Williams; J B Reed; J T Wright; T C Hart
Journal:  J Med Genet       Date:  2000-12       Impact factor: 6.318

4.  Free-thiol Cys331 exposed during activation process is critical for native tetramer structure of cathepsin C (dipeptidyl peptidase I).

Authors:  Martin Horn; Miroslav Baudys; Zdenek Voburka; Ivan Kluh; Jirí Vondrásek; Michael Mares
Journal:  Protein Sci       Date:  2002-04       Impact factor: 6.725

5.  Structure of human dipeptidyl peptidase I (cathepsin C): exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases.

Authors:  D Turk; V Janjić; I Stern; M Podobnik; D Lamba; S W Dahl; C Lauritzen; J Pedersen; V Turk; B Turk
Journal:  EMBO J       Date:  2001-12-03       Impact factor: 11.598

Review 6.  Proteolytic-antiproteolytic balance and its regulation in carcinogenesis.

Authors:  Elzbieta Skrzydlewska; Mariola Sulkowska; Mariusz Koda; Stanislaw Sulkowski
Journal:  World J Gastroenterol       Date:  2005-03-07       Impact factor: 5.742

Review 7.  More than just an enzyme: Dipeptidyl peptidase-4 (DPP-4) and its association with diabetic kidney remodelling.

Authors:  Shreyasi Gupta; Utpal Sen
Journal:  Pharmacol Res       Date:  2019-08-08       Impact factor: 7.658

8.  Identification, immunolocalization, and characterization analyses of an exopeptidase of papain superfamily, (cathepsin C) from Clonorchis sinensis.

Authors:  Pei Liang; Lei He; Yanquan Xu; Xueqing Chen; Yan Huang; Mengyu Ren; Chi Liang; Xuerong Li; Jin Xu; Gang Lu; Xinbing Yu
Journal:  Parasitol Res       Date:  2014-08-21       Impact factor: 2.289

9.  'Patchiness' and basic cancer research: unravelling the proteases.

Authors:  Surinder M Soond; Maria V Kozhevnikova; Andrey A Zamyatnin
Journal:  Cell Cycle       Date:  2019-06-24       Impact factor: 4.534

10.  Expression and purification of active recombinant cathepsin C (dipeptidyl aminopeptidase I) of kuruma prawn Marsupenaeus japonicus in insect cells.

Authors:  Gao-Feng Qiu; Hai-Yang Feng; Keisuke Yamano
Journal:  J Biomed Biotechnol       Date:  2009-08-18
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