Literature DB >> 7649

A model independent method for estimating the in vivo release rate constant of a drug from its oral formulations.

D P Vaughan.   

Abstract

A simple equation by which the first-order release rate constant of a drug from its oral formulation can be calculated is derived. The derivation is independent of any hypothetical concepts of drug distribution or elimination.

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Year:  1976        PMID： 7649     DOI： 10.1111/j.2042-7158.1976.tb02775.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN： 0022-3573            Impact factor:   3.765


  3 in total

1.  Correlation of in vitro release rate and in vivo absorption characteristics of four chlorpheniramine maleate extended-release formulations.

Authors:  P Mojaverian; E Radwanski; C C Lin; P Cho; W A Vadino; J M Rosen
Journal:  Pharm Res       Date:  1992-04       Impact factor: 4.200

2.  A model-independent proof of Dost's law of corresponding areas.

Authors:  D P Vaughan
Journal:  J Pharmacokinet Biopharm       Date:  1977-06

3.  Regulatory Experience with In Vivo In Vitro Correlations (IVIVC) in New Drug Applications.

Authors:  Sandra Suarez-Sharp; Min Li; John Duan; Heta Shah; Paul Seo
Journal:  AAPS J       Date:  2016-08-01       Impact factor: 4.009
  3 in total

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