Literature DB >> 764844

Reduced lethality in mice receiving a combined dose of cyclophosphamide and busulphan.

J L Millar, B N Hudspith, N M Blackett.   

Abstract

Animals treated with a sufficiently high dose of busulphan die about 14 days later from bone marrow failure. A single, appropriately timed injection of cyclophosphamide can save these mice. The nature of this protection is shown to be the cyclophosphamide induced elaboration of a humoral factor which stimulates haemopoietic recovery.

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Year:  1975        PMID： 764844      PMCID： PMC2024837          DOI： 10.1038/bjc.1975.149

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  14 in total

1.  Increased survival in irradiated animals treated with bacterial endotoxins.

Authors:  W W SMITH; I M ALDERMAN; R E GILLESPIE
Journal:  Am J Physiol       Date:  1957-10

2.  The effect of cyclophosphamide on hematopoietic stem cells.

Authors:  W Fried; C Johnson
Journal:  Radiat Res       Date:  1968-12       Impact factor: 2.841

3.  Survival of rat bone marrow cells after treatment with myleran and endoxan.

Authors:  A Dunjic; A M Cuvelier
Journal:  Exp Hematol       Date:  1973       Impact factor: 3.084

4.  Accelerated regeneration of transplanted hematopoietic stem cells in irradiated mice pretreated with cyclophosphamide.

Authors:  S A Gregory; W Fried; W H Knospe; F E Trobaugh
Journal:  Blood       Date:  1971-02       Impact factor: 22.113

5.  Granulocyte colony stimulating factor. I. Response to acute granulocytopenia.

Authors:  R K Shadduck; N G Nagabhushanam
Journal:  Blood       Date:  1971-11       Impact factor: 22.113

6.  On mouse strain differences in radiation resistance: hematopoietic death and the endogenous colony-forming unit.

Authors:  J M Yuhas; J B Storer
Journal:  Radiat Res       Date:  1969-09       Impact factor: 2.841

7.  Effect of endotoxin on granulopoiesis and colony-stimulating factor.

Authors:  P Quesenberry; A Morley; F Stohlman; K Rickard; D Howard; M Smith
Journal:  N Engl J Med       Date:  1972-02-03       Impact factor: 91.245

8.  Effects of bacterial endotoxin on the occurrence of spleen colonies in irradiated mice.

Authors:  W W Smith; G Brecher; R A Budd; S Fred
Journal:  Radiat Res       Date:  1966-03       Impact factor: 2.841

9.  The cloning of normal "mast" cells in tissue culture.

Authors:  D H Pluznik; L Sachs
Journal:  J Cell Physiol       Date:  1965-12       Impact factor: 6.384

10.  The effect of a homologous series of dimethane-sulphonoxy-alkanes on haemopoietic colony forming units in the rat.

Authors:  C D Dunn; L A Elson
Journal:  Chem Biol Interact       Date:  1970-12       Impact factor: 5.192
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  15 in total

Review 1.  Molecular mechanisms of drug resistance.

Authors:  J D Hayes; C R Wolf
Journal:  Biochem J       Date:  1990-12-01       Impact factor: 3.857

Review 2.  Animal models for acquired bone marrow failure syndromes.

Authors:  Jichun Chen
Journal:  Clin Med Res       Date:  2005-05

3.  Cyclophosphamide and cis-dichlorodiammine platinum (11). Nonempiric scheduling to spare dose-limiting tissues in the rat.

Authors:  K D Tew; D M Taylor
Journal:  Cancer Chemother Pharmacol       Date:  1980       Impact factor: 3.333

Review 4.  [Hematopoietic stimulation for enhanced bone marrow regeneration after chemotherapy (author's transl)].

Authors:  L Labedzki; D Noack
Journal:  Klin Wochenschr       Date:  1980-03-03

Review 5.  The impact of redox and thiol status on the bone marrow: Pharmacological intervention strategies.

Authors:  Christina L Grek; Danyelle M Townsend; Kenneth D Tew
Journal:  Pharmacol Ther       Date:  2010-10-15       Impact factor: 12.310

6.  Influence of scheduling on two-drug combinations of alkylating agents in vivo.

Authors:  B A Teicher; S A Holden; S M Jones; J P Eder; T S Herman
Journal:  Cancer Chemother Pharmacol       Date:  1989       Impact factor: 3.333

7.  The effect of treatment with high dose melphalan, cisplatin or carboplatin on levels of glutathione in plasma, erythrocytes, mononuclear cells and urine.

Authors:  L Hogarth; M English; L Price; R Wyllie; A D Pearson; A G Hall
Journal:  Cancer Chemother Pharmacol       Date:  1996       Impact factor: 3.333

8.  Metabolism of high doses of cyclophosphamide.

Authors:  R A Milsted; M Jarman
Journal:  Cancer Chemother Pharmacol       Date:  1982       Impact factor: 3.333

9.  Primitive Sca-1 Positive Bone Marrow HSC in Mouse Model of Aplastic Anemia: A Comparative Study through Flowcytometric Analysis and Scanning Electron Microscopy.

Authors:  Sumanta Chatterjee; Pratima Basak; Prosun Das; Madhurima Das; Jacintha Archana Pereira; Ranjan Kumar Dutta; Malay Chaklader; Samaresh Chaudhuri; Sujata Law
Journal:  Stem Cells Int       Date:  2009-10-28       Impact factor: 5.443

10.  Priming with low doses of methyl-CCNU reduce the toxicity of high doses of methyl-CCNU and melphalan, and increase the lifespan of mice implanted with Lewis lung carcinoma.

Authors:  A Zimber; K Perk; I Livnat
Journal:  Br J Cancer       Date:  1988-03       Impact factor: 7.640
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