OBJECTIVE: To determine which anthropometric methods of assessing body fat distribution are the most predictive of the insulin resistance of aging. DESIGN: Commonly used indices of regional adiposity were correlated with whole-body insulin sensitivity in 55 men and 29 women (age range 18-80 years). MEASUREMENTS: Insulin sensitivity (SI, minimal model), waist and hip girths, waist-to-hip ratios, conicity index, skinfolds, body fat percentage, maximal oxygen consumption. RESULTS: There was a wide disparity in the strength of relationships between commonly used anthropometric indices of fat distribution and whole-body insulin sensitivity. In both sexes minimal waist girth, however, was the primary variable in multivariate regression analysis, accounting for approximately 37% of the variance in SI. CONCLUSION: These findings indicate that anthropometric measures of regional adiposity are not interchangeable and/or equivalent when attempting to discern relationships between body fat distribution, insulin sensitivity, and aging.
OBJECTIVE: To determine which anthropometric methods of assessing body fat distribution are the most predictive of the insulin resistance of aging. DESIGN: Commonly used indices of regional adiposity were correlated with whole-body insulin sensitivity in 55 men and 29 women (age range 18-80 years). MEASUREMENTS: Insulin sensitivity (SI, minimal model), waist and hip girths, waist-to-hip ratios, conicity index, skinfolds, body fat percentage, maximal oxygen consumption. RESULTS: There was a wide disparity in the strength of relationships between commonly used anthropometric indices of fat distribution and whole-body insulin sensitivity. In both sexes minimal waist girth, however, was the primary variable in multivariate regression analysis, accounting for approximately 37% of the variance in SI. CONCLUSION: These findings indicate that anthropometric measures of regional adiposity are not interchangeable and/or equivalent when attempting to discern relationships between body fat distribution, insulin sensitivity, and aging.
Authors: Erica P Gunderson; David R Jacobs; Vicky Chiang; Cora E Lewis; Ailin Tsai; Charles P Quesenberry; Stephen Sidney Journal: Am J Obstet Gynecol Date: 2009-06-26 Impact factor: 8.661
Authors: Erica P Gunderson; Susana L Matias; Shanta R Hurston; Kathryn G Dewey; Assiamira Ferrara; Charles P Quesenberry; Joan C Lo; Barbara Sternfeld; Joseph V Selby Journal: BMC Public Health Date: 2011-12-23 Impact factor: 3.295