Literature DB >> 7647341

Prognostic significance of laminin production in relation with its receptor expression in human breast carcinomas.

R Pellegrini1, S Martignone, E Tagliabue, D Belotti, R Bufalino, N Cascinelli, S Ménard, M I Colnaghi.   

Abstract

Laminin is a basement membrane glycoprotein whose expression has been widely related to cancer progression. Laminin production by primary breast carcinomas was investigated using immunohistochemistry on archival specimens from a retrospective series with long term follow-up. Laminin production was found to be independent of the clinical and pathological variables analyzed, whereas a statistically significant direct association with the expression of the laminin receptor and a negative association with the differentiation-related antigen Ca-MBr8 were observed. Survival analysis indicated that laminin positivity by itself has no prognostic significance. However, when analyzed together with the laminin receptor expression, laminin was associated with a good prognosis in receptor-negative tumors and with the worst prognosis in receptor-positive tumors.

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Year:  1995        PMID： 7647341     DOI： 10.1007/bf00668209

Source DB:  PubMed          Journal:  Breast Cancer Res Treat        ISSN： 0167-6806            Impact factor:   4.872


  23 in total

1.  Characterization of two monoclonal antibodies directed against the 67 kDa high affinity laminin receptor and application for the study of breast carcinoma progression.

Authors:  S Martignone; R Pellegrini; E Villa; N N Tandon; A Mastroianni; E Tagliabue; S Ménard; M I Colnaghi
Journal:  Clin Exp Metastasis       Date:  1992-11       Impact factor: 5.150

Review 2.  Integrins.

Authors:  E Ruoslahti
Journal:  J Clin Invest       Date:  1991-01       Impact factor: 14.808

3.  Laminin increases the release of type IV collagenase from malignant cells.

Authors:  T Turpeenniemi-Hujanen; U P Thorgeirsson; C N Rao; L A Liotta
Journal:  J Biol Chem       Date:  1986-02-05       Impact factor: 5.157

4.  Co-ordinate expression of the alpha-6 integrin laminin receptor sub-unit and laminin in breast cancer.

Authors:  A J D'Ardenne; P I Richman; M A Horton; A E Mcaulay; S Jordan
Journal:  J Pathol       Date:  1991-11       Impact factor: 7.996

5.  Laminin and fibronectin in adenoid cystic carcinoma.

Authors:  A J d'Ardenne; P Kirkpatrick; C A Wells; J D Davies
Journal:  J Clin Pathol       Date:  1986-02       Impact factor: 3.411

6.  Metastatic potential of murine fibrosarcoma cells is influenced by cell surface laminin.

Authors:  H L Malinoff; J P McCoy; J Varani; M S Wicha
Journal:  Int J Cancer       Date:  1984-05-15       Impact factor: 7.396

7.  Alteration of laminin production in small-cell lung carcinoma: possible correlation with the absence of the basement membrane.

Authors:  A Mastroianni; L Invernizzi; E Tagliabue; G Fassina; A Albini; S Ménard; M I Colnaghi
Journal:  Tumour Biol       Date:  1993

8.  Prognostic significance of the 67-kilodalton laminin receptor expression in human breast carcinomas.

Authors:  S Martignone; S Ménard; R Bufalino; N Cascinelli; R Pellegrini; E Tagliabue; S Andreola; F Rilke; M I Colnaghi
Journal:  J Natl Cancer Inst       Date:  1993-03-03       Impact factor: 13.506

9.  Enhancement of metastatic potential of murine and human melanoma cells by laminin receptor peptide G: attachment of cancer cells to subendothelial matrix as a pathway for hematogenous metastasis.

Authors:  G Taraboletti; D Belotti; R Giavazzi; M E Sobel; V Castronovo
Journal:  J Natl Cancer Inst       Date:  1993-02-03       Impact factor: 13.506

10.  Study of the biological and prognostic significance of the antigen CaMBr8 on breast carcinoma.

Authors:  P Facheris; F Perrone; S Ménard; S Andreola; P Bazzini; R Bufalino; S Canevari; N Cascinelli; E Colzani; G Di Fronzo
Journal:  Br J Cancer       Date:  1992-03       Impact factor: 7.640
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  7 in total

1.  Vimentin and laminin expression is associated with basal-like phenotype in both sporadic and BRCA1-associated breast carcinomas.

Authors:  Socorro María Rodríguez-Pinilla; David Sarrió; Emiliano Honrado; Gema Moreno-Bueno; David Hardisson; Francisco Calero; Javier Benítez; José Palacios
Journal:  J Clin Pathol       Date:  2006-11-14       Impact factor: 3.411

2.  Expression of extracellular matrix proteins in cervical squamous cell carcinoma--a clinicopathological study.

Authors:  I Goldberg; B Davidson; L Lerner-Geva; W H Gotlieb; G Ben-Baruch; I Novikov; J Kopolovic
Journal:  J Clin Pathol       Date:  1998-10       Impact factor: 3.411

3.  Comprehensive proteomic analysis of nonintegrin laminin receptor interacting proteins.

Authors:  Lisa Venticinque; Daniel Meruelo
Journal:  J Proteome Res       Date:  2012-08-29       Impact factor: 4.466

4.  Detection of laminin in serum and ascites from patients with epithelial ovarian tumor.

Authors:  Yongli Chu; Yuanxian Yang; Meihua Lin; Zehua Wang
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2002

5.  An adiponectin paralog protein, CTRP6 decreased the proliferation and invasion activity of oral squamous cell carcinoma cells: possible interaction with laminin receptor pathway.

Authors:  Kimika Hano; Kiichi Hatano; Chiemi Saigo; Yusuke Kito; Toshiyuki Shibata; Tamotsu Takeuchi
Journal:  Mol Biol Rep       Date:  2019-06-28       Impact factor: 2.316

6.  Laminin activates the p185HER2 oncoprotein and mediates growth inhibition of breast carcinoma cells.

Authors:  E Tagliabue; E Ardini; R Pellegrini; M Campiglio; R Bufalino; M Jeschke; B Groner; M I Colnaghi; S Ménard
Journal:  Br J Cancer       Date:  1996-11       Impact factor: 7.640

7.  Systematic analysis of tumour cell-extracellular matrix adhesion identifies independent prognostic factors in breast cancer.

Authors:  Jason R Todd; Karen A Ryall; Simon Vyse; Jocelyn P Wong; Rachael C Natrajan; Yinyin Yuan; Aik-Choon Tan; Paul H Huang
Journal:  Oncotarget       Date:  2016-09-27
  7 in total

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