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Literature DB >> 7647085

Psychosis in Apert's syndrome with partial agenesis of the corpus callosum.

Abstract

A 19-year-old male with Apert's syndrome developed psychotic symptoms that responded to haloperidol. He was also found to have partial agenesis of the corpus callosum and enlarged lateral ventricles on a head CT scan. The implications of these findings in the context of psychotic symptoms are discussed. There are no previous reports of psychosis in patients with Apert's syndrome.

Entities: Chemical Disease Species

Mesh：

Substances：
Haloperidol

Year: 1995 PMID： 7647085 PMCID： PMC1188707

Source DB: PubMed Journal: J Psychiatry Neurosci ISSN： 1180-4882 Impact factor: 6.186

11 in total

1. Increased prevalence of the cavum septum pellucidum in magnetic resonance scans and post-mortem brains of schizophrenic patients.

Authors: G Degreef; B Bogerts; P Falkai; B Greve; G Lantos; M Ashtari; J Lieberman
Journal: Psychiatry Res Date: 1992-05 Impact factor: 3.222

Review 2. Organic psychosis.

Authors: J L Cummings
Journal: Psychosomatics Date: 1988 Impact factor: 2.386

Psychosis in Apert's syndrome with partial agenesis of the corpus callosum.

1. Increased prevalence of the cavum septum pellucidum in magnetic resonance scans and post-mortem brains of schizophrenic patients.

Review 2. Organic psychosis.

3. Gross pathology of the cerebellum in patients diagnosed and treated as functional psychiatric disorders.

Review 4. The central nervous system in the Apert syndrome.

5. Neuropsychiatric disturbances following brainstem lesions.

Review 6. Selected clinical research involving the central nervous system.

7. The late-onset psychoses. Clinical and diagnostic features.

8. Developmental abnormalities of the corpus callosum in schizophrenia.

9. Agenesis of the corpus callosum and limbic malformation in Apert syndrome (type I acrocephalosyndactyly).

10. Cavum vergae. Association with neurologic abnormality and diagnosis by magnetic resonance imaging.

1. White matter abnormalities and animal models examining a putative role of altered white matter in schizophrenia.