Literature DB >> 7642380

[The tuberculid concept from the current viewpoint].

O Braun-Falco1, P Thomas.   

Abstract

The concept of tuberculid was introduced by Darier in 1896. In contrast to "true" cutaneous tuberculosis, properties of the tuberculids were explained by an hyperergic response to myobacteria or their fragments released from a different site of manifest or passed tuberculous infection. Key features include a strongly positive tuberculin skin test, evidence of concomitant manifest or past tuberculosis, and prompt response to antituberculous therapy. The inability to culture M. tuberculosis or to demonstrate it microscopically from lesional biopsies, together with reports on tuberculid-like eruptions after BCG vaccination, supports this concept. Clinical manifestations are lichen scrophulosorum, papulo-necrotic tuberculids and erythema induratum of Bazin. The existence of tuberculids has been questioned, however, because the clinical and histological appearances are not always specific. An increasing number of case reports on tuberculids, new immunological tests and molecular biology-based techniques for the detection of mycobacteria have shed new light on the tuberculid concept.

Entities:  

Mesh:

Year:  1995        PMID: 7642380     DOI: 10.1007/s001050050270

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  4 in total

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Authors:  Satyendra Kumar Singh; Tulika Rai
Journal:  Indian Dermatol Online J       Date:  2014-01

3.  Immune-mediated tuberculous uveitis - A rare association with papulonecrotic tuberculid.

Authors:  Prince Yuvraj Singh; Preema Sinha; Sukriti Baveja; Aradhana Sood
Journal:  Indian J Ophthalmol       Date:  2019-07       Impact factor: 1.848

4.  Papulonecrotic Tuberculid with Positive Acid-fast Bacilli.

Authors:  Ren Jun; Liu Xiao-Kun; Pan Chao; Li Xin-Sheng; Wang Xiao-Hui; Yan Xin; Chen Mei-Hua; Zeng Kang
Journal:  Indian J Dermatol       Date:  2013-01       Impact factor: 1.494

  4 in total

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