| Literature DB >> 7642308 |
K I Gaede1, E Baumeister, J Heesemann.
Abstract
Lewis rats experimentally infected with Yersinia enterocolitica O8 develop Yersinia-induced arthritis (YIA), which resembles very much reactive arthritis in humans. To investigate the involvement of serum complement in induction and maintenance of YIA, we decomplementated Yersinia-infected Lewis rats by treatment with cobra venom factor starting on day 7 after infection (prearthritic state). Reduction of serum complement activity in vivo by cobra venom factor treatment coincided with suppression of YIA clinically and histomorphologically.Entities:
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Year: 1995 PMID: 7642308 PMCID: PMC173512 DOI: 10.1128/iai.63.9.3697-3701.1995
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441