OBJECTIVE: To assess the value of hysterosalpingography (HSG) in diagnosing tubal patency and peritubal adhesions using laparoscopy with chromopertubation as the gold standard. DESIGN: Meta-analysis of 20 studies comparing HSG and laparoscopy for tubal patency and peritubal adhesions. PATIENTS: Four thousand one hundred seventy-nine patients with infertility in 20 studies. INTERVENTION: Hysterosalpingography and diagnostic laparoscopy as part of infertility workup. MAIN OUTCOME MEASURE: Tubal patency and peritubal adhesions. RESULTS: For tubal patency the reported sensitivity and specificity differed between studies. In a subset of studies that evaluated HSG and laparoscopy independently, a point estimate of 0.65 for sensitivity and 0.83 for specificity was calculated. For peritubal adhesions a summary receiver operating characteristic curve could be estimated. CONCLUSIONS: Although HSG is of limited use for detecting tubal patency because of its low sensitivity, its high specificity makes it a useful test for ruling in tubal obstruction. For the evaluation of peritubal adhesions HSG is not reliable.
OBJECTIVE: To assess the value of hysterosalpingography (HSG) in diagnosing tubal patency and peritubal adhesions using laparoscopy with chromopertubation as the gold standard. DESIGN: Meta-analysis of 20 studies comparing HSG and laparoscopy for tubal patency and peritubal adhesions. PATIENTS: Four thousand one hundred seventy-nine patients with infertility in 20 studies. INTERVENTION: Hysterosalpingography and diagnostic laparoscopy as part of infertility workup. MAIN OUTCOME MEASURE: Tubal patency and peritubal adhesions. RESULTS: For tubal patency the reported sensitivity and specificity differed between studies. In a subset of studies that evaluated HSG and laparoscopy independently, a point estimate of 0.65 for sensitivity and 0.83 for specificity was calculated. For peritubal adhesions a summary receiver operating characteristic curve could be estimated. CONCLUSIONS: Although HSG is of limited use for detecting tubal patency because of its low sensitivity, its high specificity makes it a useful test for ruling in tubal obstruction. For the evaluation of peritubal adhesions HSG is not reliable.
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Authors: Allison K Rodgers; Nicole M Budrys; Siqi Gong; Jie Wang; Alan Holden; Robert S Schenken; Guangming Zhong Journal: Fertil Steril Date: 2011-07-13 Impact factor: 7.329
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