Literature DB >> 7641586

Mechanisms of acetaminophen toxicity: immunochemical detection of drug-protein adducts.

J A Hinson1, N R Pumford, D W Roberts.   

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Year:  1995        PMID： 7641586     DOI： 10.3109/03602539509029816

Source DB:  PubMed          Journal:  Drug Metab Rev        ISSN： 0360-2532            Impact factor:   4.518


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  17 in total

1.  Novel protective mechanisms for S-adenosyl-L-methionine against acetaminophen hepatotoxicity: improvement of key antioxidant enzymatic function.

Authors:  James Michael Brown; John G Ball; Michael Scott Wright; Stephanie Van Meter; Monica A Valentovic
Journal:  Toxicol Lett       Date:  2012-06-05       Impact factor: 4.372

2.  Inhibition of carbamyl phosphate synthetase-I and glutamine synthetase by hepatotoxic doses of acetaminophen in mice.

Authors:  S Gupta; L K Rogers; S K Taylor; C V Smith
Journal:  Toxicol Appl Pharmacol       Date:  1997-10       Impact factor: 4.219

Review 3.  Acetaminophen Toxicity: A History of Serendipity and Unintended Consequences.

Authors:  William M Lee
Journal:  Clin Liver Dis (Hoboken)       Date:  2020-10-07

4.  Apoptotic events induced by high glucose in human hepatoma HepG2 cells involve endoplasmic reticulum stress and MAPK's activation.

Authors:  Qiaoling Jiang; Yujun Yuan; Jiali Zhou; Yan Wu; Qing Zhou; Shuyu Gui; Yuan Wang
Journal:  Mol Cell Biochem       Date:  2014-10-09       Impact factor: 3.396

5.  Development of polyclonal antibodies for the detection of styrene oxide modified proteins.

Authors:  Wei Yuan; Jouku Chung; Shirley Gee; Bruce D Hammock; Jiang Zheng
Journal:  Chem Res Toxicol       Date:  2007-02-01       Impact factor: 3.739

6.  Adenovirus mediated overexpression of CYP2E1 increases sensitivity of HepG2 cells to acetaminophen induced cytotoxicity.

Authors:  Jingxiang Bai; Arthur I Cederbaum
Journal:  Mol Cell Biochem       Date:  2004-07       Impact factor: 3.396

7.  Acetaminophen-associated hepatic injury: evaluation of acetaminophen protein adducts in children and adolescents with acetaminophen overdose.

Authors:  L P James; E V Capparelli; P M Simpson; L Letzig; D Roberts; J A Hinson; G L Kearns; J L Blumer; J E Sullivan
Journal:  Clin Pharmacol Ther       Date:  2008-10-15       Impact factor: 6.875

8.  Hit-to-Lead Studies for the Antimalarial Tetrahydroisoquinolone Carboxanilides.

Authors:  David M Floyd; Philip Stein; Zheng Wang; Jian Liu; Steve Castro; Julie A Clark; Michele Connelly; Fangyi Zhu; Gloria Holbrook; Amy Matheny; Martina S Sigal; Jaeki Min; Rajkumar Dhinakaran; Senthil Krishnan; Sridevi Bashyum; Spencer Knapp; R Kiplin Guy
Journal:  J Med Chem       Date:  2016-08-25       Impact factor: 7.446

9.  Liver delivery of NO by NCX-1000 protects against acute liver failure and mitochondrial dysfunction induced by APAP in mice.

Authors:  Stefano Fiorucci; Elisabetta Antonelli; Eleonora Distrutti; Andrea Mencarelli; Silvana Farneti; Piero Del Soldato; Antonio Morelli
Journal:  Br J Pharmacol       Date:  2004-09       Impact factor: 8.739

10.  Chromatin breakdown by deoxyribonuclease1 promotes acetaminophen-induced liver necrosis: an ultrastructural and histochemical study on male CD-1 mice.

Authors:  Monika Jacob; Hans Georg Mannherz; Markus Napirei
Journal:  Histochem Cell Biol       Date:  2007-05-25       Impact factor: 4.304
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