Literature DB >> 7638986

Involvement of the 4q21 region in human malignant melanomas: cytogenetic and immunocytochemical characterization of three primary cell cultures.

P Grammatico1, M Roccella, C Catricalà, F Roccella, S Bucher, C Mordenti, A Amantea, C Di Rosa, G Del Porto.   

Abstract

The GRO1 oncogene (melanoma growth-stimulating activity alpha) has been localized in region 4q21. The involvement of this chromosomal region in clonal aberrations found in primary melanoma cell cultures could have an important role in the etiology and pathogenesis of this tumor. We characterized three primary cell cultures obtained from different patients, each of which showed clonal chromosomal aberrations involving the 4q21 region.

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Year:  1995        PMID： 7638986     DOI： 10.1007/bf00299156

Source DB:  PubMed          Journal:  World J Surg        ISSN： 0364-2313            Impact factor:   3.352


  3 in total

1.  Mouse melanoma growth stimulatory activity gene (Mgsa) is polymorphic and syntenic with the W, patch, rumpwhite, and recessive spotting loci on chromosome 5.

Authors:  A Y Sakaguchi; P A Lalley; G G Choudhury; L Martinez; E S Han; A M Killary; S L Naylor; L M Wang
Journal:  Genomics       Date:  1989-10       Impact factor: 5.736

2.  Identification of three related human GRO genes encoding cytokine functions.

Authors:  S Haskill; A Peace; J Morris; S A Sporn; A Anisowicz; S W Lee; T Smith; G Martin; P Ralph; R Sager
Journal:  Proc Natl Acad Sci U S A       Date:  1990-10       Impact factor: 11.205

3.  A detailed multipoint map of human chromosome 4 provides evidence for linkage heterogeneity and position-specific recombination rates.

Authors:  K H Buetow; R Shiang; P Yang; Y Nakamura; G M Lathrop; R White; J J Wasmuth; S Wood; L D Berdahl; N J Leysens
Journal:  Am J Hum Genet       Date:  1991-05       Impact factor: 11.025
  3 in total
  1 in total

1.  Comparative genomic hybridization in a case of melanoma that loses expression of S100, HMB45, Melan A and tyrosinase in metastasis.

Authors:  Ruifeng Guo; Xianfu Wang; Jie Chen; Ellizabeth Gillies; Kar-Ming Fung; Shibo Li; Lewis A Hassell
Journal:  Int J Clin Exp Pathol       Date:  2013-12-15
  1 in total

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