Literature DB >> 7638906

Genetic approaches to nuclear pore structure and function.

V Doye1, E C Hurt.   

Abstract

The major features of nucleocytoplasmic transport through nuclear pore complexes are conserved from yeast to humans. This transport machinery, which includes the 125 MDa nuclear pore complex structure, has been molecularly dissected in the yeast Saccharomyces cerevisiae by genetic approaches. Here, we summarize the genetic analyses used to elucidate structure-function relationships within this large supramolecular assembly.

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Year:  1995        PMID： 7638906     DOI： 10.1016/s0168-9525(00)89057-5

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  43 in total

1.  The recruitment of RNA polymerase I on rDNA is mediated by the interaction of the A43 subunit with Rrn3.

Authors:  G Peyroche; P Milkereit; N Bischler; H Tschochner; P Schultz; A Sentenac; C Carles; M Riva
Journal:  EMBO J       Date:  2000-10-16       Impact factor: 11.598

2.  members only encodes a Drosophila nucleoporin required for rel protein import and immune response activation.

Authors:  A E Uv; P Roth; N Xylourgidis; A Wickberg; R Cantera; C Samakovlis
Journal:  Genes Dev       Date:  2000-08-01       Impact factor: 11.361

3.  Nuclear transport defects and nuclear envelope alterations are associated with mutation of the Saccharomyces cerevisiae NPL4 gene.

Authors:  C DeHoratius; P A Silver
Journal:  Mol Biol Cell       Date:  1996-11       Impact factor: 4.138

4.  Nup93, a vertebrate homologue of yeast Nic96p, forms a complex with a novel 205-kDa protein and is required for correct nuclear pore assembly.

Authors:  P Grandi; T Dang; N Pané; A Shevchenko; M Mann; D Forbes; E Hurt
Journal:  Mol Biol Cell       Date:  1997-10       Impact factor: 4.138

5.  Nup154, a new Drosophila gene essential for male and female gametogenesis is related to the nup155 vertebrate nucleoporin gene.

Authors:  S Gigliotti; G Callaini; S Andone; M G Riparbelli; R Pernas-Alonso; G Hoffmann; F Graziani; C Malva
Journal:  J Cell Biol       Date:  1998-09-07       Impact factor: 10.539

Review 6.  The nuclear pore complex.

Authors:  A Heese-Peck; N V Raikhel
Journal:  Plant Mol Biol       Date:  1998-09       Impact factor: 4.076

7.  cut11(+): A gene required for cell cycle-dependent spindle pole body anchoring in the nuclear envelope and bipolar spindle formation in Schizosaccharomyces pombe.

Authors:  R R West; E V Vaisberg; R Ding; P Nurse; J R McIntosh
Journal:  Mol Biol Cell       Date:  1998-10       Impact factor: 4.138

8.  In vitro reconstitution of a heterotrimeric nucleoporin complex consisting of recombinant Nsp1p, Nup49p, and Nup57p.

Authors:  N L Schlaich; M Häner; A Lustig; U Aebi; E C Hurt
Journal:  Mol Biol Cell       Date:  1997-01       Impact factor: 4.138

Review 9.  The nuclear pore complex: understanding its function through structural insight.

Authors:  Martin Beck; Ed Hurt
Journal:  Nat Rev Mol Cell Biol       Date:  2016-12-21       Impact factor: 94.444

10.  Members of the RSC chromatin-remodeling complex are required for maintaining proper nuclear envelope structure and pore complex localization.

Authors:  Laura C Titus; T Renee Dawson; Deborah J Rexer; Kathryn J Ryan; Susan R Wente
Journal:  Mol Biol Cell       Date:  2010-01-28       Impact factor: 4.138
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