Literature DB >> 7638605

Behavioral effects and gene delivery in a rat model of Parkinson's disease.

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Year:  1995        PMID： 7638605     DOI： 10.1126/science.7638605

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


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  7 in total

1.  Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer.

Authors:  Deniz Kirik; Biljana Georgievska; Corinna Burger; Christian Winkler; Nicholas Muzyczka; Ronald J Mandel; Anders Bjorklund
Journal:  Proc Natl Acad Sci U S A       Date:  2002-03-26       Impact factor: 11.205

2.  Correction of a rat model of Parkinson's disease by coexpression of tyrosine hydroxylase and aromatic amino acid decarboxylase from a helper virus-free herpes simplex virus type 1 vector.

Authors:  Mei Sun; Guo-Rong Zhang; Lingxin Kong; Courtney Holmes; Xiaodan Wang; Wei Zhang; David S Goldstein; Alfred I Geller
Journal:  Hum Gene Ther       Date:  2003-03-20       Impact factor: 5.695

3.  Double transduction with GTP cyclohydrolase I and tyrosine hydroxylase is necessary for spontaneous synthesis of L-DOPA by primary fibroblasts.

Authors:  C Bencsics; S R Wachtel; S Milstien; K Hatakeyama; J B Becker; U J Kang
Journal:  J Neurosci       Date:  1996-07-15       Impact factor: 6.167

4.  Characterization of intrastriatal recombinant adeno-associated virus-mediated gene transfer of human tyrosine hydroxylase and human GTP-cyclohydrolase I in a rat model of Parkinson's disease.

Authors:  R J Mandel; K G Rendahl; S K Spratt; R O Snyder; L K Cohen; S E Leff
Journal:  J Neurosci       Date:  1998-06-01       Impact factor: 6.167

5.  Coexpression of tyrosine hydroxylase, GTP cyclohydrolase I, aromatic amino acid decarboxylase, and vesicular monoamine transporter 2 from a helper virus-free herpes simplex virus type 1 vector supports high-level, long-term biochemical and behavioral correction of a rat model of Parkinson's disease.

Authors:  Mei Sun; Lingxin Kong; Xiaodan Wang; Courtney Holmes; Qingsheng Gao; Guo-Rong Zhang; Josef Pfeilschifter; David S Goldstein; Alfred I Geller
Journal:  Hum Gene Ther       Date:  2004-12       Impact factor: 5.695

Review 6.  An update on gene therapy in Parkinson's disease.

Authors:  Jennifer Witt; William J Marks
Journal:  Curr Neurol Neurosci Rep       Date:  2011-08       Impact factor: 5.081

7.  Long-term doxycycline-controlled expression of human tyrosine hydroxylase after direct adenovirus-mediated gene transfer to a rat model of Parkinson's disease.

Authors:  O Corti; A Sánchez-Capelo; P Colin; N Hanoun; M Hamon; J Mallet
Journal:  Proc Natl Acad Sci U S A       Date:  1999-10-12       Impact factor: 11.205
  7 in total

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