Literature DB >> 7633662

A case report of synovial sarcoma with translocation (X;18). Application of fluorescence in situ hybridization to paraffin-embedded tissue.

K Nagao1, Y Gomyo, H Ito, K Yamamoto, H Yoshida.   

Abstract

A 57-year-old female patient with synovial sarcoma in her right foot had a chromosome abnormality defined as translocation (X;18). The tumour was located in the subcutis, and histological investigation showed monophasic proliferation of oval to spindle-shaped cells with a fascicular arrangement lacking an epithelial component. Immunostaining disclosed no cytokeratin or epithelial membrane antigen in tumour cells. Karyotypic analysis revealed translocation (X;18) in addition to other nonspecific aberrations. Fluorescence in situ hybridization was carried out on paraffin-embedded tissue, using DNA probes for the centromeres of chromosomes X and 18 with whole chromosome painting probes for X and 18. The free nuclei showed two signals at a rate of 83-85% with the X and 18 centromeric probes, in contrast to three signals at a rate of 68-70% with the X and 18 painting probes.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 7633662     DOI： 10.1007/bf00193176

Source DB:  PubMed          Journal:  Virchows Arch        ISSN： 0945-6317            Impact factor:   4.064


  18 in total

1.  Translocation X;18 in synovial sarcoma.

Authors:  C Turc-Carel; P Dal Cin; J Limon; F Li; A A Sandberg
Journal:  Cancer Genet Cytogenet       Date:  1986-09

2.  The t(X;18)(p11.2;q11.2) translocation found in human synovial sarcomas involves two distinct loci on the X chromosome.

Authors:  J M Shipley; J Clark; A J Crew; S Birdsall; P J Rocques; S Gill; J Chelly; A P Monaco; S Abe; B A Gusterson
Journal:  Oncogene       Date:  1994-05       Impact factor: 9.867

3.  Involvement of chromosome X in primary cytogenetic change in human neoplasia: nonrandom translocation in synovial sarcoma.

Authors:  C Turc-Carel; P Dal Cin; J Limon; U Rao; F P Li; J M Corson; R Zimmerman; D M Parry; J M Cowan; A A Sandberg
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205

4.  Application of long-term collagenase disaggregation for the cytogenetic analysis of human solid tumors.

Authors:  J Limon; P Dal Cin; A A Sandberg
Journal:  Cancer Genet Cytogenet       Date:  1986-12

5.  Identification of a yeast artificial chromosome (YAC) spanning the synovial sarcoma-specific t(X;18)(p11.2;q11.2) breakpoint.

Authors:  B de Leeuw; W Berger; R J Sinke; R F Suijkerbuijk; S Gilgenkrantz; M T Geraghty; D Valle; A P Monaco; H Lehrach; H H Ropers
Journal:  Genes Chromosomes Cancer       Date:  1993-03       Impact factor: 5.006

6.  Localization of X chromosome short arm markers relative to synovial sarcoma- and renal adenocarcinoma-associated translocation breakpoints.

Authors:  R J Sinke; B de Leeuw; H A Janssen; D O Weghuis; R F Suijkerbuijk; A M Meloni; S Gilgenkrantz; W Berger; H H Ropers; A A Sandberg
Journal:  Hum Genet       Date:  1993-10-01       Impact factor: 4.132

7.  Cardiac synovial sarcoma with translocation (X;18) associated with asbestos exposure.

Authors:  C M Karn; M A Socinski; J A Fletcher; J M Corson; J E Craighead
Journal:  Cancer       Date:  1994-01-01       Impact factor: 6.860

8.  Localization of the synovial sarcoma t(X;18)(p11.2;q11.2) breakpoint by fluorescence in situ hybridization.

Authors:  J C Knight; B R Reeves; L Kearney; A P Monaco; H Lehrach; C S Cooper
Journal:  Hum Mol Genet       Date:  1992-11       Impact factor: 6.150

Review 9.  Chromosomes in the diagnosis of soft tissue tumors. I. Synovial sarcoma.

Authors:  P Dal Cin; U Rao; S Jani-Sait; C Karakousis; A A Sandberg
Journal:  Mod Pathol       Date:  1992-07       Impact factor: 7.842

10.  Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.

Authors:  D Pinkel; T Straume; J W Gray
Journal:  Proc Natl Acad Sci U S A       Date:  1986-05       Impact factor: 11.205
View more
  4 in total

1.  A practical approach to the clinical diagnosis of Ewing's sarcoma/primitive neuroectodermal tumour and other small round cell tumours sharing EWS rearrangement using new fluorescence in situ hybridisation probes for EWSR1 on formalin fixed, paraffin wax embedded tissue.

Authors:  U Yamaguchi; T Hasegawa; Y Morimoto; U Tateishi; M Endo; F Nakatani; A Kawai; H Chuman; Y Beppu; M Endo; H Kurotaki; K Furuta
Journal:  J Clin Pathol       Date:  2005-10       Impact factor: 3.411

2.  Use of nonbreakpoint DNA probes to detect the t(X;18) in interphase cells from synovial sarcoma: implications for detection of diagnostic tumor translocations.

Authors:  M Zilmer; C P Harris; D S Steiner; L F Meisner
Journal:  Am J Pathol       Date:  1998-05       Impact factor: 4.307

3.  Interphase fluorescence in situ hybridization and reverse transcription polymerase chain reaction as a diagnostic aid for synovial sarcoma.

Authors:  J Shipley; J Crew; S Birdsall; S Gill; J Clark; C Fisher; A Kelsey; T Nojima; H Sonobe; C Cooper; B Gusterson
Journal:  Am J Pathol       Date:  1996-02       Impact factor: 4.307

4.  Chromosomal translocation t(X;18) in human synovial sarcomas analyzed by fluorescence in situ hybridization using paraffin-embedded tissue.

Authors:  K Nagao; H Ito; H Yoshida
Journal:  Am J Pathol       Date:  1996-02       Impact factor: 4.307
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.