Literature DB >> 7631644

Effects of cocaine on cortisol secretion in humans.

C M Heesch1, B H Negus, J H Keffer, R W Snyder, R C Risser, E J Eichhorn.   

Abstract

The effects of acute cocaine administration on the pituitary adrenal axis in humans without a history of drug abuse are unknown. The authors studied 12 male volunteers twice in a double-blinded, placebo-controlled, randomized fashion. After intranasal administration of 2 mg/kg cocaine, cortisol levels were significantly higher than after placebo administration. The authors concluded that acute administration of cocaine to humans increases cortisol secretion.

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Year:  1995        PMID： 7631644     DOI： 10.1097/00000441-199508000-00004

Source DB:  PubMed          Journal:  Am J Med Sci        ISSN： 0002-9629            Impact factor:   2.378


  21 in total

1.  Hypothalamic-pituitary-adrenal axis and sympatho-adreno-medullary responses during stress-induced and drug cue-induced cocaine craving states.

Authors:  Rajita Sinha; Makram Talih; Robert Malison; Ned Cooney; George M Anderson; Mary Jeanne Kreek
Journal:  Psychopharmacology (Berl)       Date:  2003-07-04       Impact factor: 4.530

Review 2.  Making a bad thing worse: adverse effects of stress on drug addiction.

Authors:  Jessica N Cleck; Julie A Blendy
Journal:  J Clin Invest       Date:  2008-02       Impact factor: 14.808

Review 3.  Drugs and HPA axis.

Authors:  Alberto Giacinto Ambrogio; Francesca Pecori Giraldi; Francesco Cavagnini
Journal:  Pituitary       Date:  2008       Impact factor: 4.107

Review 4.  Oral candidiasis, HIV, and saliva glucocorticoids.

Authors:  C O Enwonwu; V I Meeks
Journal:  Am J Pathol       Date:  1996-04       Impact factor: 4.307

5.  Prefrontal-Bed Nucleus Circuit Modulation of a Passive Coping Response Set.

Authors:  Shane B Johnson; Eric B Emmons; Ryan T Lingg; Rachel M Anderson; Sara A Romig-Martin; Ryan T LaLumiere; Nandakumar S Narayanan; Victor Viau; Jason J Radley
Journal:  J Neurosci       Date:  2018-12-20       Impact factor: 6.167

6.  Interactive role of human immunodeficiency virus type 1 (HIV-1) clade-specific Tat protein and cocaine in blood-brain barrier dysfunction: implications for HIV-1-associated neurocognitive disorder.

Authors:  Nimisha Gandhi; Zainulabedin M Saiyed; Jessica Napuri; Thangavel Samikkannu; Pichili V B Reddy; Marisela Agudelo; Pradnya Khatavkar; Shailendra K Saxena; Madhavan P N Nair
Journal:  J Neurovirol       Date:  2010-07       Impact factor: 2.643

Review 7.  Systems-level view of cocaine addiction: the interconnection of the immune and nervous systems.

Authors:  Christina C Marasco; Cody R Goodwin; Danny G Winder; Nicole L Schramm-Sapyta; John A McLean; John P Wikswo
Journal:  Exp Biol Med (Maywood)       Date:  2014-06-05

8.  Dysregulation of diurnal cortisol secretion affects abstinence induction during a lead-in period of a clinical trial for depressed cocaine-dependent patients.

Authors:  Wilfrid Noel Raby; Lisa Sanfilippo; Martina Pavlicova; Kenneth M Carpenter; Andrew Glass; Chukwudi Onyemekwu; Eric Roginek; Edward V Nunes
Journal:  Am J Addict       Date:  2013-05-30

Review 9.  Chronic stress, drug use, and vulnerability to addiction.

Authors:  Rajita Sinha
Journal:  Ann N Y Acad Sci       Date:  2008-10       Impact factor: 5.691

10.  Self-administration of fentanyl, cocaine and ketamine: effects on the pituitary-adrenal axis in rhesus monkeys.

Authors:  Jillian H Broadbear; Gail Winger; James H Woods
Journal:  Psychopharmacology (Berl)       Date:  2004-04-28       Impact factor: 4.530
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