Event-related potentials to airway occlusion in young and old subjects.

Event-related potentials (ERPs) were recorded to both inspiratory and expiratory airway occlusion in young (21-28 years) and old (55-67 years) subjects under both attend and ignore conditions. Early and late components of the ERP (N1, P2, N2, P3) were observed to both types of occlusions in both conditions. Variations in these components were consistent in both direction and degree with those observed in oddball tasks employing exteroceptive stimuli. ERPs for breathing may serve to clarify sensory attributes of respiratory stimuli in humans and to identify central processing abnormalities in patient populations.