| Literature DB >> 7628989 |
J Holton1, D Vaira, M Menegatti, L Barbara.
Abstract
Forty strains of Helicobacter pylori had an MIC(50) of 4 mg/L of the non-absorbably antibiotic, rifaximin. Neither synergy nor antagonism was demonstrated when the drug was combined with ampicillin, metronidazole and omeprazole and the rate of spontaneous mutation was less than 1 in 10(8). With these in-vitro characteristics, rifaximin should now be assessed for clinical efficacy.Entities:
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Year: 1995 PMID： 7628989 DOI： 10.1093/jac/35.4.545
Source DB: PubMed Journal: J Antimicrob Chemother ISSN： 0305-7453 Impact factor: 5.790