Literature DB >> 7628709

A Saccharomyces cerevisiae gene essential for viability has been conserved in evolution.

T Rinaldi1, M Bolotin-Fukuhara, L Frontali.   

Abstract

To identify the gene coding for the endonuclease which processes the 3' end of mitochondrial (mt) tRNA transcripts in Saccharomyces cerevisiae, nuclear mutations able to complement a mt mutant (Ts932) defective for this process were isolated and analyzed. One of these mutants exhibited a growth defect both on respiratory and fermentable media. Complementation of this phenotype with a S. cerevisiae centrometric wild-type genomic library has allowed us to identify a new essential S. cerevisiae gene strongly conserved in various eukaryotic organisms.

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Year:  1995        PMID： 7628709     DOI： 10.1016/0378-1119(95)00212-o

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  10 in total

1.  The regulatory particle of the Saccharomyces cerevisiae proteasome.

Authors:  M H Glickman; D M Rubin; V A Fried; D Finley
Journal:  Mol Cell Biol       Date:  1998-06       Impact factor: 4.272

Review 2.  Roles of COP9 signalosome in cancer.

Authors:  Mong-Hong Lee; Ruiying Zhao; Liem Phan; Sai-Ching J Yeung
Journal:  Cell Cycle       Date:  2011-09-15       Impact factor: 4.534

3.  Proteasome mutants, pre4-2 and ump1-2, suppress the essential function but not the mitochondrial RNase P function of the Saccharomyces cerevisiae gene RPM2.

Authors:  M S Lutz; S R Ellis; N C Martin
Journal:  Genetics       Date:  2000-03       Impact factor: 4.562

4.  HER2-Akt signaling in regulating COP9 signalsome subunit 6 and p53.

Authors:  Yuwen Xue; Jian Chen; Hyun-Ho Choi; Liem Phan; Ping-Chieh Chou; Ruiying Zhao; Huiling Yang; Janice Santiago; Mo Liu; Giselle E Yeung; Sai-Ching J Yeung; Mong-Hong Lee
Journal:  Cell Cycle       Date:  2012-10-24       Impact factor: 4.534

5.  CSN6 positively regulates c-Jun in a MEKK1-dependent manner.

Authors:  Jihyun Shin; Liem Phan; Jian Chen; Zhimin Lu; Mong-Hong Lee
Journal:  Cell Cycle       Date:  2015-08-03       Impact factor: 4.534

6.  A mutation in a novel yeast proteasomal gene, RPN11/MPR1, produces a cell cycle arrest, overreplication of nuclear and mitochondrial DNA, and an altered mitochondrial morphology.

Authors:  T Rinaldi; C Ricci; D Porro; M Bolotin-Fukuhara; L Frontali
Journal:  Mol Biol Cell       Date:  1998-10       Impact factor: 4.138

7.  ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer Development.

Authors:  Lekun Fang; Weisi Lu; Hyun Ho Choi; Sai-Ching J Yeung; Jung-Yu Tung; Chwan-Deng Hsiao; Enrique Fuentes-Mattei; David Menter; Chuangqi Chen; Lei Wang; Jianping Wang; Mong-Hong Lee
Journal:  Cancer Cell       Date:  2015-08-10       Impact factor: 31.743

8.  CDK inhibitor p57 (Kip2) is negatively regulated by COP9 signalosome subunit 6.

Authors:  Bo Chen; Ruiying Zhao; Chun-Hui Su; Monica Linan; Chieh Tseng; Liem Phan; Lekuan Fang; Heng-Yin Yang; Huiling Yang; Wenqian Wang; Xiaoyin Xu; Nan Jiang; Shouliang Cai; Feng Jin; Sai-Ching J Yeung; Mong-Hong Lee
Journal:  Cell Cycle       Date:  2012-11-27       Impact factor: 4.534

9.  Base-CP proteasome can serve as a platform for stepwise lid formation.

Authors:  Zanlin Yu; Nurit Livnat-Levanon; Oded Kleifeld; Wissam Mansour; Mark A Nakasone; Carlos A Castaneda; Emma K Dixon; David Fushman; Noa Reis; Elah Pick; Michael H Glickman
Journal:  Biosci Rep       Date:  2015-01-27       Impact factor: 3.840

10.  COP9 signalosome subunit 6 (CSN6) regulates E6AP/UBE3A in cervical cancer.

Authors:  Shujun Gao; Lekun Fang; Liem Minh Phan; Aiham Qdaisat; Sai-Ching J Yeung; Mong-Hong Lee
Journal:  Oncotarget       Date:  2015-09-29
  10 in total

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