Literature DB >> 7627937

Chromosome 12 abnormalities in malignant ovarian germ cell tumors.

E Rodriguez1, J Melamed, V Reuter, R S Chaganti.   

Abstract

We analyzed 3 cases of malignant ovarian germ cell tumors (MOGCTs), comprising 1 dysgerminoma and 2 immature teratomas, by banded chromosome analysis and by in situ hybridization (ISH) using a chromosome 12p painting probe. We found evidence of 12p abnormalities in two of them. A possible common genetic pathway of origin of a subset of MOGCTs with testicular germ cell tumors (TGCTs) is discussed.

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Year:  1995        PMID： 7627937     DOI： 10.1016/0165-4608(95)00067-y

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  3 in total

1.  Primary amenorrhoea due to ovarian dysgenesis: a previously undescribed chromosome 12 abnormality.

Authors:  Paul Grant; David Lipscomb
Journal:  BMJ Case Rep       Date:  2011-03-03

2.  Molecular characterization of uterine and ovarian tumors with mixed epithelial and germ cell features confirms frequent somatic derivation.

Authors:  Stephanie L Skala; Chia-Jen Liu; Aaron M Udager; Andrew P Sciallis
Journal:  Mod Pathol       Date:  2020-05-13       Impact factor: 7.842

3.  Overexpression of karyopherin 2 in human ovarian malignant germ cell tumor correlates with poor prognosis.

Authors:  Li He; Hui Ding; Jian-Hua Wang; Yun Zhou; Li Li; Yan-Hong Yu; Long Huang; Wei-Hua Jia; Musheng Zeng; Jing-Ping Yun; Rong-Zhen Luo; Min Zheng
Journal:  PLoS One       Date:  2012-09-04       Impact factor: 3.240
  3 in total

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