OBJECTIVES: The aim of the present study was to evaluate microcirculartory changes of the postocclusive reactive hyperaemia test measured with Laser Doppler fluxmetry to detect results of arterial reconstructions. DESIGN: Prospective open study. SETTING: Vascular laboratory of a University Hospital. MATERIAL: Sixty patients with peripheral arterial occlusive disease who underwent infrainguinal reconstruction were examined the day before and 1-2 days after surgery. CHIEF OUTCOME MEASURES: The values were obtained during postocclusive reactive hyperaemia induced by release of a 3 min arterial occlusion with a cuff at ankle level with the laser Doppler probe placed dorsally on the first toe. The alterations after surgery in these hyperaemia parameters were compared to changes in ankle/brachial index and clinical improvement at 30 days postoperatively. MAIN RESULTS: Patients improved by surgery according to ankle/brachial index had significantly reduced time to peak (p < 0.001) and significantly increased resting flux value (p < 0.05) and peak flux value (p < 0.05). There was a significant correlation between the change after surgery in time to peak flux and increment of ankle/brachial index (r = 0.63, p < 0.001). CONCLUSIONS: Changes in reactive hyperaemia values as measured with laser Doppler fluxmetry, especially the time to peak flux, seem to detect circulatory changes caused by arterial reconstructions.
OBJECTIVES: The aim of the present study was to evaluate microcirculartory changes of the postocclusive reactive hyperaemia test measured with Laser Doppler fluxmetry to detect results of arterial reconstructions. DESIGN: Prospective open study. SETTING: Vascular laboratory of a University Hospital. MATERIAL: Sixty patients with peripheral arterial occlusive disease who underwent infrainguinal reconstruction were examined the day before and 1-2 days after surgery. CHIEF OUTCOME MEASURES: The values were obtained during postocclusive reactive hyperaemia induced by release of a 3 min arterial occlusion with a cuff at ankle level with the laser Doppler probe placed dorsally on the first toe. The alterations after surgery in these hyperaemia parameters were compared to changes in ankle/brachial index and clinical improvement at 30 days postoperatively. MAIN RESULTS:Patients improved by surgery according to ankle/brachial index had significantly reduced time to peak (p < 0.001) and significantly increased resting flux value (p < 0.05) and peak flux value (p < 0.05). There was a significant correlation between the change after surgery in time to peak flux and increment of ankle/brachial index (r = 0.63, p < 0.001). CONCLUSIONS: Changes in reactive hyperaemia values as measured with laser Doppler fluxmetry, especially the time to peak flux, seem to detect circulatory changes caused by arterial reconstructions.
Authors: Alba Carreras; Shelley X Zhang; Eduard Peris; Zhuanhong Qiao; Alex Gileles-Hillel; Richard C Li; Yang Wang; David Gozal Journal: Sleep Date: 2014-11-01 Impact factor: 5.849
Authors: Leila Kheirandish-Gozal; Rakesh Bhattacharjee; Jinkwan Kim; Heather B Clair; David Gozal Journal: Am J Respir Crit Care Med Date: 2010-03-04 Impact factor: 21.405