Literature DB >> 7627551

Ion-channel gating. Twist to open.

M S Sansom1.   

Abstract

Three-dimensional images of the open state of the nicotinic acetylcholine receptor have been obtained at 9 A resolution. Comparison with the closed state reveals the structural basis of channel gating.

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Year:  1995        PMID： 7627551     DOI： 10.1016/s0960-9822(95)00076-5

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  8 in total

1.  M2 pore mutations convert the glycine receptor channel from being anion- to cation-selective.

Authors:  A Keramidas; A J Moorhouse; C R French; P R Schofield; P H Barry
Journal:  Biophys J       Date:  2000-07       Impact factor: 4.033

2.  Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism.

Authors:  Antoine Taly; Marc Delarue; Thomas Grutter; Michael Nilges; Nicolas Le Novère; Pierre-Jean Corringer; Jean-Pierre Changeux
Journal:  Biophys J       Date:  2005-04-01       Impact factor: 4.033

3.  Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer.

Authors:  Gisela D Cymes; Claudio Grosman
Journal:  Nat Struct Mol Biol       Date:  2008-03-30       Impact factor: 15.369

4.  The pore domain of the nicotinic acetylcholine receptor: molecular modeling, pore dimensions, and electrostatics.

Authors:  R Sankararamakrishnan; C Adcock; M S Sansom
Journal:  Biophys J       Date:  1996-10       Impact factor: 4.033

5.  Simulation studies of alamethicin-bilayer interactions.

Authors:  P C Biggin; J Breed; H S Son; M S Sansom
Journal:  Biophys J       Date:  1997-02       Impact factor: 4.033

6.  Water in channel-like cavities: structure and dynamics.

Authors:  M S Sansom; I D Kerr; J Breed; R Sankararamakrishnan
Journal:  Biophys J       Date:  1996-02       Impact factor: 4.033

7.  Gating mechanism of the influenza A M2 channel revealed by 1D and 2D IR spectroscopies.

Authors:  Joshua Manor; Prabuddha Mukherjee; Yu-Shan Lin; Hadas Leonov; James L Skinner; Martin T Zanni; Isaiah T Arkin
Journal:  Structure       Date:  2009-02-13       Impact factor: 5.006

8.  pH-driven helix rotations in the influenza M2 H+ channel: a potential gating mechanism.

Authors:  Hadas Leonov; Isaiah T Arkin
Journal:  Eur Biophys J       Date:  2009-04-03       Impact factor: 1.733
  8 in total

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