Literature DB >> 7626105

Early detection of catabolic state via change in 13C/12C ratios of blood proteins.

K A Hatch1, K A Sacksteder, I W Treichel, M E Cook, W P Porter.   

Abstract

We find that induction of catabolic state changes the ratios of carbon 13 to carbon 12 in blood proteins. Diet can be inferred in growing chicks by feather carbon isotope ratios. This suggests an approach for early detection of catabolic state induced in patients with HIV, cancers that induce catabolism, infection onset, sepsis, kidney and liver disease, malnutrition and dietary problems. The technique would also be useful in animal husbandry.

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Year:  1995        PMID： 7626105     DOI： 10.1006/bbrc.1995.2030

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  7 in total

1.  Novel diagnostics of metabolic dysfunction detected in breath and plasma by selective isotope-assisted labeling.

Authors:  Julia A Haviland; Marco Tonelli; Dermot T Haughey; Warren P Porter; Fariba M Assadi-Porter
Journal:  Metabolism       Date:  2012-02-02       Impact factor: 8.694

2.  Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome.

Authors:  Leah D Whigham; Daniel E Butz; Hesam Dashti; Marco Tonelli; Luann K Johnson; Mark E Cook; Warren P Porter; Hamid R Eghbalnia; John L Markley; Steven R Lindheim; Dale A Schoeller; David H Abbott; Fariba M Assadi-Porter
Journal:  Curr Metabolomics       Date:  2014

3.  Breath carbon stable isotope ratios identify changes in energy balance and substrate utilization in humans.

Authors:  L D Whigham; D E Butz; L K Johnson; D A Schoeller; D H Abbott; W P Porter; M E Cook
Journal:  Int J Obes (Lond)       Date:  2014-01-20       Impact factor: 5.095

4.  Changes in the natural abundance of 13CO2/12CO2 in breath due to lipopolysacchride-induced acute phase response.

Authors:  Daniel E Butz; Mark E Cook; Hamid R Eghbalnia; Fariba Assadi-Porter; Warren P Porter
Journal:  Rapid Commun Mass Spectrom       Date:  2009-12       Impact factor: 2.419

5.  Do stable isotopes reflect nutritional stress? Results from a laboratory experiment on song sparrows.

Authors:  Bethany Kempster; Liana Zanette; Fred J Longstaffe; Scott A MacDougall-Shackleton; John C Wingfield; Michael Clinchy
Journal:  Oecologia       Date:  2006-11-11       Impact factor: 3.298

6.  Effects of nutritional restriction on nitrogen and carbon stable isotopes in growing seabirds.

Authors:  Cory T Williams; C Loren Buck; Justine Sears; Alexander S Kitaysky
Journal:  Oecologia       Date:  2007-04-04       Impact factor: 3.298

7.  A modern baseline for the paired isotopic analysis of skin and bone in terrestrial mammals.

Authors:  Sean P Doherty; Matthew J Collins; Alison J T Harris; Ainara Sistiaga; Jason Newton; Michelle M Alexander
Journal:  R Soc Open Sci       Date:  2022-01-12       Impact factor: 2.963
  7 in total

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