Literature DB >> 7625999

Differential calcium dependence in the activation of c-Jun kinase and mitogen-activated protein kinase by muscarinic acetylcholine receptors in rat 1a cells.

F M Mitchell1, M Russell, G L Johnson.   

Abstract

Carbachol stimulation of the muscarinic acetylcholine m1 receptor (m1R), stably expressed in Rat 1a fibroblasts, resulted in a calcium-dependent activation of c-Jun kinase (JNK). Stimulation of the muscarinic acetylcholine m2 receptor (m2R), stably expressed in Rat 1a fibroblasts, resulted in a G1-mediated activation of JNK that was weak relative to that observed with the m1R. Chelation of calcium inhibited the m2R-mediated activation of JNK but not the robust m2R stimulation of mitogen-activated protein kinase (MAPK) activity. These findings demonstrate a role for the second messenger, calcium, in the differential regulation of the activity of JNK and MAPK in Rat 1a cells.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 7625999      PMCID： PMC1135742          DOI： 10.1042/bj3090381

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  27 in total

1.  Reconstitutively active G protein-coupled receptors purified from baculovirus-infected insect cells.

Authors:  E M Parker; K Kameyama; T Higashijima; E M Ross
Journal:  J Biol Chem       Date:  1991-01-05       Impact factor: 5.157

2.  Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes.

Authors:  J S Gutkind; E A Novotny; M R Brann; K C Robbins
Journal:  Proc Natl Acad Sci U S A       Date:  1991-06-01       Impact factor: 11.205

Review 3.  Inositol trisphosphate and calcium signalling.

Authors:  M J Berridge
Journal:  Nature       Date:  1993-01-28       Impact factor: 49.962

4.  Subcellular patterns of calcium release determined by G protein-specific residues of muscarinic receptors.

Authors:  J Lechleiter; S Girard; D Clapham; E Peralta
Journal:  Nature       Date:  1991-04-11       Impact factor: 49.962

5.  Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells.

Authors:  L M Graves; K E Bornfeldt; E W Raines; B C Potts; S G Macdonald; R Ross; E G Krebs
Journal:  Proc Natl Acad Sci U S A       Date:  1993-11-01       Impact factor: 11.205

6.  Involvement of Ras and Raf in the Gi-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase.

Authors:  S Winitz; M Russell; N X Qian; A Gardner; L Dwyer; G L Johnson
Journal:  J Biol Chem       Date:  1993-09-15       Impact factor: 5.157

7.  Transforming G protein-coupled receptors potently activate JNK (SAPK). Evidence for a divergence from the tyrosine kinase signaling pathway.

Authors:  O A Coso; M Chiariello; G Kalinec; J M Kyriakis; J Woodgett; J S Gutkind
Journal:  J Biol Chem       Date:  1995-03-10       Impact factor: 5.157

8.  Activation of MAP kinases by calcium-dependent and calcium-independent pathways. Stimulation by thapsigargin and epidermal growth factor.

Authors:  T S Chao; K L Byron; K M Lee; M Villereal; M R Rosner
Journal:  J Biol Chem       Date:  1992-10-05       Impact factor: 5.157

9.  Reconstitution of agonist-stimulated phosphatidylinositol 4,5-bisphosphate hydrolysis using purified m1 muscarinic receptor, Gq/11, and phospholipase C-beta 1.

Authors:  G Berstein; J L Blank; A V Smrcka; T Higashijima; P C Sternweis; J H Exton; E M Ross
Journal:  J Biol Chem       Date:  1992-04-25       Impact factor: 5.157

10.  cAMP antagonizes p21ras-directed activation of extracellular signal-regulated kinase 2 and phosphorylation of mSos nucleotide exchange factor.

Authors:  B M Burgering; G J Pronk; P C van Weeren; P Chardin; J L Bos
Journal:  EMBO J       Date:  1993-11       Impact factor: 11.598
View more
  11 in total

1.  Glutamate, but not dopamine, stimulates stress-activated protein kinase and AP-1-mediated transcription in striatal neurons.

Authors:  M A Schwarzschild; R L Cole; S E Hyman
Journal:  J Neurosci       Date:  1997-05-15       Impact factor: 6.167

2.  Differential regulation of extracellular signal-regulated protein kinase 1 and Jun N-terminal kinase 1 by Ca2+ and protein kinase C in endothelin-stimulated Rat-1 cells.

Authors:  K Cadwallader; J Beltman; F McCormick; S Cook
Journal:  Biochem J       Date:  1997-02-01       Impact factor: 3.857

3.  M1 muscarinic receptors modify oxidative stress response to acetaminophen-induced acute liver injury.

Authors:  Nathalie H Urrunaga; Ravirajsinh N Jadeja; Vikrant Rachakonda; Daniel Ahmad; Leon P McLean; Kunrong Cheng; Vijay Shah; William S Twaddell; Jean-Pierre Raufman; Sandeep Khurana
Journal:  Free Radic Biol Med       Date:  2014-10-31       Impact factor: 7.376

4.  Differential effects of opioid and adrenergic agonists on proliferation in a cultured cell line.

Authors:  D Agarwal; J A Glasel
Journal:  Cell Prolif       Date:  1999-08       Impact factor: 6.831

5.  Arachidonic acid activates c-jun N-terminal kinase through NADPH oxidase in rabbit proximal tubular epithelial cells.

Authors:  X L Cui; J G Douglas
Journal:  Proc Natl Acad Sci U S A       Date:  1997-04-15       Impact factor: 11.205

6.  Regulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G-protein-linked muscarinic acetylcholine receptors.

Authors:  P G Wylie; R A Challiss; J L Blank
Journal:  Biochem J       Date:  1999-03-15       Impact factor: 3.857

7.  Ca(2+)-dependent activation of c-jun NH(2)-terminal kinase in primary rabbit proximal tubule epithelial cells.

Authors:  X L Cui; W W Jin; Y X Ding; L D Alexander; U Hopfer; J G Douglas
Journal:  Am J Physiol Cell Physiol       Date:  2000-08       Impact factor: 4.249

8.  Growth inhibitory properties of endothelin-1 in activated human hepatic stellate cells: a cyclic adenosine monophosphate-mediated pathway. Inhibition of both extracellular signal-regulated kinase and c-Jun kinase and upregulation of endothelin B receptors.

Authors:  A Mallat; A M Préaux; C Serradeil-Le Gal; D Raufaste; C Gallois; D A Brenner; C Bradham; J Maclouf; V Iourgenko; L Fouassier; D Dhumeaux; P Mavier; S Lotersztajn
Journal:  J Clin Invest       Date:  1996-12-15       Impact factor: 14.808

9.  Effects of heavy metals on mitogen-activated protein kinase pathways.

Authors:  Masato Matsuoka; Hideki Igisu
Journal:  Environ Health Prev Med       Date:  2002-01       Impact factor: 3.674

10.  Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascade.

Authors:  H Enslen; H Tokumitsu; P J Stork; R J Davis; T R Soderling
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-01       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.