| Literature DB >> 7624341 |
P van Gelderen1, N F Ramsey, G Liu, J H Duyn, J A Frank, D R Weinberger, C T Moonen.
Abstract
Functional magnetic resonance imaging (fMRI) is a tool for mapping brain function that utilizes neuronal activity-induced changes in blood oxygenation. An efficient three-dimensional fMRI method is presented for imaging brain activity on conventional, widely available, 1.5-T scanners, without additional hardware. This approach uses large magnetic susceptibility weighting based on the echo-shifting principle combined with multiple gradient echoes per excitation. Motor stimulation, induced by self-paced finger tapping, reliably produced significant signal increase in the hand region of the contralateral primary motor cortex in every subject tested.Entities:
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Year: 1995 PMID： 7624341 PMCID： PMC41439 DOI： 10.1073/pnas.92.15.6906
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205