| Literature DB >> 7624013 |
K Otsuguro1, T Asano, T Ohta, S Ito, Y Nakazato.
Abstract
Adenosine 5'-triphosphate (ATP) evoked an inward current in whole-cell voltage-clamped adrenal chromaffin cells of the guinea pig. The reversal potential (Erev) of ATP-evoked current was about 0 mV in normal external solution and was shifted towards negative potentials by substituting Tris+ or sucrose, but not Ca2+, for the extracellular Na+. This current was mediated by the activation of non-selective cation channels and had some different properties from nicotinic current. It is suggested that these channels may function as a part of the ATP-induced Ca2+ influx pathway in guinea pig chromaffin cells.Entities:
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Year: 1995 PMID： 7624013 DOI： 10.1016/0304-3940(95)11359-5
Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046