Literature DB >> 7623485

Analgesic effect of Dioclea grandiflora constituents in rodents.

J S Batista1, R N Almeida, J Bhattacharyya.   

Abstract

An aqueous fraction and dioclein (5,2',5'-trihydroxy-6,7-dimethoxyflavanone) obtained from the ethanolic extract of the Dioclea grandiflora were tested for their analgesic effect in mice and rats employing acetic-induced writhing and tail flick tests, respectively. When administered intraperitoneally the two agents exhibited significant analgesic effects. The activity of both dioclein and aqueous fraction apparently involves an opiate-like mechanism, since their analgesic action was attenuated by naloxone pretreatment.

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Year:  1995        PMID： 7623485     DOI： 10.1016/0378-8741(94)01217-n

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  5 in total

1.  Antinociceptive and toxicological effects of Dioclea grandiflora seed pod in mice.

Authors:  Rita de Cássia da Silveira e Sá; Leandra Eugênia Gomes de Oliveira; Franklin Ferreira de Farias Nóbrega; Jnanabrata Bhattacharyya; Reinaldo Nóbrega de Almeida
Journal:  J Biomed Biotechnol       Date:  2010-03-25

2.  Antinociceptive activity of the chloroform fraction of Dioclea virgata (Rich.) Amshoff (Fabaceae) in mice.

Authors:  Vanine Gomes Mota; Fabíola Lélis de Carvalho; Liana Clébia Soares Lima de Morais; Jnanabrata Bhattacharyya; Reinaldo Nóbrega de Almeida; Jacicarlos Lima de Alencar
Journal:  J Biomed Biotechnol       Date:  2011-07-05

3.  Cyclodextrin-complexed Ocimum basilicum leaves essential oil increases Fos protein expression in the central nervous system and produce an antihyperalgesic effect in animal models for fibromyalgia.

Authors:  Simone S Nascimento; Adriano A S Araújo; Renan G Brito; Mairim R Serafini; Paula P Menezes; Josimari M DeSantana; Waldecy Lucca; Pericles B Alves; Arie F Blank; Rita C M Oliveira; Aldeidia P Oliveira; Ricardo L C Albuquerque; Jackson R G S Almeida; Lucindo J Quintans
Journal:  Int J Mol Sci       Date:  2014-12-29       Impact factor: 5.923

4.  Stilbenes as κ-selective, non-nitrogenous opioid receptor antagonists.

Authors:  Alyssa M Hartung; John A Beutler; Hernán A Navarro; David F Wiemer; Jeffrey D Neighbors
Journal:  J Nat Prod       Date:  2014-01-23       Impact factor: 4.050

5.  Pharmacological evaluation of Mallotus philippinensis (Lam.) Muell.-Arg. fruit hair extract for anti-inflammatory, analgesic and hypnotic activity.

Authors:  Mayank Gangwar; Manish Kumar Gautam; Shivani Ghildiyal; Gopal Nath; Raj Kumar Goel
Journal:  J Intercult Ethnopharmacol       Date:  2015-12-22
  5 in total

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