Literature DB >> 7623482

Crude extracts of hepatoprotective plants, Solanum nigrum and Cichorium intybus inhibit free radical-mediated DNA damage.

S Sultana1, S Perwaiz, M Iqbal, M Athar.   

Abstract

The presence of plant extracts of Solanum nigrum and Cichorium intybus in the reaction mixture containing calf thymus DNA and free radical generating system protect DNA against oxidative damage to its deoxyribose sugar moiety. The effect was dependent on the concentration of plant extracts. However, the effect of Cichorium intybus was much pronounced as compared to the effect of Solanum nigrum. These studies suggest that the observed hepatoprotective effect of these crude plant extracts may be due to their ability to suppress the oxidative degradation of DNA in the tissue debris.

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Year:  1995        PMID： 7623482     DOI： 10.1016/0378-8741(94)01214-k

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  16 in total

1.  Antioxidant and antihyperlipidemic effect of Solanum nigrum fruit extract on the experimental model against chronic ethanol toxicity.

Authors:  Vadivel Arulmozhi; Mani Krishnaveni; Kandhan Karthishwaran; Ganesan Dhamodharan; Sankaran Mirunalini
Journal:  Pharmacogn Mag       Date:  2010-02-13       Impact factor: 1.085

2.  Antioxidant activity ofcurculigo orchioides in carbon tetrachloride-induced hepatopathy in rats.

Authors:  M R Venukumar; M S Latha
Journal:  Indian J Clin Biochem       Date:  2002-07

3.  Antioxidant effect of methanolic extract ofSolanum nigrum berries on aspirin induced gastric mucosal injury.

Authors:  Mallika Jainu; C S Shyamala Devi
Journal:  Indian J Clin Biochem       Date:  2004-01

4.  Antidiabetic Activity of Aqueous Extract of Solanum nigrum Linn Berries in Alloxan Induced Diabetic Wistar Albino Rats.

Authors:  M S Umamageswari; T M Karthikeyan; Yasmeen A Maniyar
Journal:  J Clin Diagn Res       Date:  2017-07-01

5.  Investigation of the Antioxidant and Hepatoprotective Potential of Hypericum mysorense.

Authors:  Raghu C Hariharapura; Ramamurthy Srinivasan; Godavarthi Ashok; Santoshkumar H Dongre; Hitesh V Jagani; Pottekkad Vijayan
Journal:  Antioxidants (Basel)       Date:  2014-08-12

6.  Antioxidant activity in extracts of 27 indigenous Taiwanese vegetables.

Authors:  Pi-Yu Chao; Su-Yi Lin; Kuan-Hung Lin; Yu-Fen Liu; Ju-Ing Hsu; Chi-Ming Yang; Jun-You Lai
Journal:  Nutrients       Date:  2014-05-23       Impact factor: 5.717

7.  In vivo assessment of genotoxic, antigenotoxic and anticarcinogenic activities of Solanum lycocarpum fruits glycoalkaloidic extract.

Authors:  Carla Carolina Munari; Pollyanna Francielli de Oliveira; Luis Fernando Leandro; Leandra Mara Pimenta; Natália Helen Ferreira; Juliana de Carvalho da Costa; Jairo Kenupp Bastos; Denise Crispim Tavares
Journal:  PLoS One       Date:  2014-11-18       Impact factor: 3.240

8.  Stimulatory effects of polysaccharide fraction from Solanum nigrum on RAW 264.7 murine macrophage cells.

Authors:  Faizan Naeem Razali; Amirah Ismail; Nurhayati Zainal Abidin; Adawiyah Suriza Shuib
Journal:  PLoS One       Date:  2014-10-09       Impact factor: 3.240

Review 9.  A review of hepatoprotective plants used in saudi traditional medicine.

Authors:  Abdulrahman K Al-Asmari; Abdulrahman M Al-Elaiwi; Md Tanwir Athar; Mohammad Tariq; Ahmed Al Eid; Saeed M Al-Asmary
Journal:  Evid Based Complement Alternat Med       Date:  2014-12-18       Impact factor: 2.629

Review 10.  Cichorium intybus: Traditional Uses, Phytochemistry, Pharmacology, and Toxicology.

Authors:  Renée A Street; Jasmeen Sidana; Gerhard Prinsloo
Journal:  Evid Based Complement Alternat Med       Date:  2013-11-26       Impact factor: 2.629
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