Literature DB >> 7623073

Intraoperative radiotherapy for gliomas.

T Fujiwara1, Y Honma, T Ogawa, K Irie, H Kuyama, S Nagao, H Takashima, A Hosokawa, M Ohkawa, M Tanabe.   

Abstract

Intraoperative radiotherapy (IORT) was performed in 20 of 36 patients with glioma; 11 glioblastomas, 7 malignant astrocytomas, 2 benign astrocytomas. Twenty or 25 Gy of irradiation was delivered in a single fraction intraoperatively, followed by external beam irradiation. The electron beam energy was selected so that the 80% isodose line fell at 2 or 3 cm below the residual tumor surface. Median survival time of IORT group was 14 months and that of the control group was 10 months. Difference of survival curve was significant. There were 6 incidences of complication caused by IORT; 1 radionecrosis, 1 convulsion, 1 abscess, and 3 severe brain edemas. IORT is suited for the treatment of malignant gliomas.

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Year:  1995        PMID： 7623073     DOI： 10.1007/bf01058463

Source DB:  PubMed          Journal:  J Neurooncol        ISSN： 0167-594X            Impact factor:   4.130


  9 in total

1.  Intraoperative radiation therapy for malignant glioma.

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Journal:  Neurol Med Chir (Tokyo)       Date:  1991-11       Impact factor: 1.742

Review 2.  Recurrent malignant gliomas: survival following interstitial brachytherapy with high-activity iodine-125 sources.

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Journal:  J Neurosurg       Date:  1987-12       Impact factor: 5.115

3.  Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial.

Authors:  M D Walker; E Alexander; W E Hunt; C S MacCarty; M S Mahaley; J Mealey; H A Norrell; G Owens; J Ransohoff; C B Wilson; E A Gehan; T A Strike
Journal:  J Neurosurg       Date:  1978-09       Impact factor: 5.115

4.  Computerized tomographic and pathologic studies of the untreated, quiescent, and recurrent glioblastoma multiforme.

Authors:  P C Burger; P J Dubois; S C Schold; K R Smith; G L Odom; D C Crafts; F Giangaspero
Journal:  J Neurosurg       Date:  1983-02       Impact factor: 5.115

5.  Assumptions in the radiotherapy of glioblastoma.

Authors:  F H Hochberg; A Pruitt
Journal:  Neurology       Date:  1980-09       Impact factor: 9.910

6.  Interstitial radiobrachytherapy of malignant cerebral neoplasms: rationale, methodology, prospects.

Authors:  M L Apuzzo; Z Petrovich; G Luxton; J H Jepson; D Cohen; R E Breeze
Journal:  Neurol Res       Date:  1987-06       Impact factor: 2.448

7.  A statistical study of brain tumors in Japan: general features. The Committee of the Brain Tumor Registry in Japan.

Authors: 
Journal:  Jpn J Clin Oncol       Date:  1987-03       Impact factor: 3.019

8.  Intraoperative radiotherapy for intracranial malignancies. A pilot study.

Authors:  A L Goldson; O E Streeter; E Ashayeri; J Collier-Manning; J B Barber; K J Fan
Journal:  Cancer       Date:  1984-12-01       Impact factor: 6.860

Review 9.  Malignant glioma--a nemesis which requires clinical and basic investigation in radiation oncology.

Authors:  L W Davis
Journal:  Int J Radiat Oncol Biol Phys       Date:  1989-06       Impact factor: 7.038
  9 in total
  6 in total

1.  [Value of radiosurgery in first-line therapy of glioblastoma multiforme. The Heidelberg experience and review of the literature].

Authors:  M van Kampen; R Engenhart-Cabillic; J Debus; M Fuss; B Rhein; M Wannenmacher
Journal:  Strahlenther Onkol       Date:  1998-04       Impact factor: 3.621

2.  Intra-operative electron beam radiotherapy for newly diagnosed and recurrent malignant gliomas: feasibility and long-term outcomes.

Authors:  Sergey Usychkin; Felipe Calvo; Marcos A dos Santos; José Samblás; David Ortiz de Urbina; José Carlos Bustos; José Angel Gutiérrez Diaz; Kita Sallabanda; Ana Sanz; Carmen Yélamos; Carmen Peraza; José Miguel Delgado; Hugo Marsiglia
Journal:  Clin Transl Oncol       Date:  2012-07-20       Impact factor: 3.405

3.  Intraoperative radiation therapy (IORT) for previously untreated malignant gliomas.

Authors:  Kenji Nemoto; Yoshihiro Ogawa; Haruo Matsushita; Ken Takeda; Yoshihiro Takai; Shogo Yamada; Toshihiro Kumabe
Journal:  BMC Cancer       Date:  2002-01-15       Impact factor: 4.430

4.  INTRAGO: intraoperative radiotherapy in glioblastoma multiforme—a phase I/II dose escalation study.

Authors:  Frank A Giordano; Stefanie Brehmer; Yasser Abo-Madyan; Grit Welzel; Elena Sperk; Anke Keller; Frank Schneider; Sven Clausen; Carsten Herskind; Peter Schmiedek; Frederik Wenz
Journal:  BMC Cancer       Date:  2014-12-22       Impact factor: 4.430

Review 5.  Immunotherapy Combined with Large Fractions of Radiotherapy: Stereotactic Radiosurgery for Brain Metastases-Implications for Intraoperative Radiotherapy after Resection.

Authors:  Carsten Herskind; Frederik Wenz; Frank A Giordano
Journal:  Front Oncol       Date:  2017-07-24       Impact factor: 6.244

6.  First Experience of Intraoperative Radiation Therapy in Cerebral High Grade Glioma in Iran: A Report of Three Cases and Literature Review.

Authors:  Afsoun Seddighi; Mohammad Esmaeil Akbari; Amir Saied Seddighi; Afshin Rakhsha; Marjan Vaezi; Amir Hossein Zohrevand
Journal:  Iran J Cancer Prev       Date:  2015-10-27
  6 in total

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