Literature DB >> 7623037

Patellamide F, A new cytotoxic cyclic peptide from the colonial ascidian Lissoclinum patella.

M A Rashid1, K R Gustafson, J H Cardellina, M R Boyd.   

Abstract

Cytotoxicity-directed fractionation of an organic extract of the tunicate Lissoclinum patella afforded a new cyclic octapeptide, patellamide F [1]. The structure and absolute stereochemistry of 1 were established by a combination of spectroscopic and chemical methods. Three known cyclic peptides, patellamide B [2], ulithiacyclamide, and lissoclinamide 3, were also isolated and identified.

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Year:  1995        PMID: 7623037     DOI: 10.1021/np50118a020

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


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