Literature DB >> 7622865

Monoclonal antibody mediated capsular reactions (Quellung) in Cryptococcus neoformans.

J Mukherjee1, W Cleare, A Casadevall.   

Abstract

Capsular reactions ('Quellung') visible by light microscopy were observed when capsule-binding monoclonal antibody (mAb) was added to Cryptococcus neoformans yeast cells. Capsular reactions were observed with capsule-binding IgM, IgG1, IgG2a, IgG2b, IgG3 and IgA mAbs. Scanning electron microscopy revealed that mAb binding produced a structural change in the fibrillar network of the capsule. The occurrence of capsular reactions with mAbs indicate that this phenomenon can be produced by the binding of antibody to a single epitope.

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Year:  1995        PMID： 7622865     DOI： 10.1016/0022-1759(95)00097-t

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN： 0022-1759            Impact factor:   2.303


  13 in total

1.  Melanin, melanin "ghosts," and melanin composition in Cryptococcus neoformans.

Authors:  Y Wang; P Aisen; A Casadevall
Journal:  Infect Immun       Date:  1996-07       Impact factor: 3.441

2.  A Glucuronoxylomannan Epitope Exhibits Serotype-Specific Accessibility and Redistributes towards the Capsule Surface during Titanization of the Fungal Pathogen Cryptococcus neoformans.

Authors:  Mark Probert; Xin Zhou; Margaret Goodall; Simon A Johnston; Ewa Bielska; Elizabeth R Ballou; Robin C May
Journal:  Infect Immun       Date:  2019-03-25       Impact factor: 3.441

3.  Antibody binding to Cryptococcus neoformans impairs budding by altering capsular mechanical properties.

Authors:  Radames J B Cordero; Bruno Pontes; Susana Frases; Antonio S Nakouzi; Leonardo Nimrichter; Marcio L Rodrigues; Nathan B Viana; Arturo Casadevall
Journal:  J Immunol       Date:  2012-12-10       Impact factor: 5.422

4.  Temporal behavior of capsule enlargement by Cryptococcus neoformans.

Authors:  Radames J B Cordero; Aviv Bergman; Arturo Casadevall
Journal:  Eukaryot Cell       Date:  2013-08-16

5.  In vitro and in vivo stability of a Cryptococcus neoformans [corrected] glucuronoxylomannan epitope that elicits protective antibodies.

Authors:  W Cleare; R Cherniak; A Casadevall
Journal:  Infect Immun       Date:  1999-06       Impact factor: 3.441

6.  Radiological studies reveal radial differences in the architecture of the polysaccharide capsule of Cryptococcus neoformans.

Authors:  R A Bryan; O Zaragoza; T Zhang; G Ortiz; A Casadevall; E Dadachova
Journal:  Eukaryot Cell       Date:  2005-02

7.  The monoclonal antibody against the major diagnostic antigen of Paracoccidioides brasiliensis mediates immune protection in infected BALB/c mice challenged intratracheally with the fungus.

Authors:  R Buissa-Filho; R Puccia; A F Marques; F A Pinto; J E Muñoz; J D Nosanchuk; L R Travassos; C P Taborda
Journal:  Infect Immun       Date:  2008-05-05       Impact factor: 3.441

8.  Phenotypic switching in the human pathogenic fungus Cryptococcus neoformans is associated with changes in virulence and pulmonary inflammatory response in rodents.

Authors:  D L Goldman; B C Fries; S P Franzot; L Montella; A Casadevall
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-08       Impact factor: 11.205

Review 9.  The capsule of the fungal pathogen Cryptococcus neoformans.

Authors:  Oscar Zaragoza; Marcio L Rodrigues; Magdia De Jesus; Susana Frases; Ekaterina Dadachova; Arturo Casadevall
Journal:  Adv Appl Microbiol       Date:  2009       Impact factor: 5.086

10.  Antibodies produced in response to Cryptococcus neoformans pulmonary infection in mice have characteristics of nonprotective antibodies.

Authors:  Oscar Zaragoza; Arturo Casadevall
Journal:  Infect Immun       Date:  2004-07       Impact factor: 3.441
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