Literature DB >> 7622434

Production of the new antibiotic tetrahydrokalafungin by transformants of the kalafungin producer Streptomyces tanashiensis.

S Kakinuma1, H Ikeda, Y Takada, H Tanaka, D A Hopwood, S Omura.   

Abstract

The new antibiotic tetrahydrokalafungin was produced by the transformants of kalafungin producing S. tanashiensis and kalafungin-nonproducing mutants carrying the recombinant plasmid pKU523. This plasmid consists of pKU501 (J. Antibiotics 44: 995 approximately 1005, 1991) which contains the gene cluster for kalafungin biosynthesis, and additional 5 kb stability region of SCP2*.

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Year:  1995        PMID: 7622434     DOI: 10.7164/antibiotics.48.484

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  1 in total

1.  Accumulation of a bioactive benzoisochromanequinone compound kalafungin by a wild type antitumor-medermycin-producing streptomycete strain.

Authors:  Jin Lü; Qiang He; Luyao Huang; Xiaofeng Cai; Wenwen Guo; Jing He; Lili Zhang; Aiying Li
Journal:  PLoS One       Date:  2015-02-19       Impact factor: 3.240

  1 in total

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